Incidence, Risk Factors, and Outcome of Acute Kidney Injury in the Intensive Care Unit: A Single-Center Study from Jordan.

Autor: Oweis AO; Department of Internal Medicine, Nephrology Division, Jordan University of Science and Technology, Irbid, Jordan., Alshelleh SA; Department of Internal Medicine, Nephrology Division, The University of Jordan, Amman, Jordan., Momany SM; Department of Internal Medicine, Respiratory and Critical Care Division, Jordan University of Science and Technology, Irbid, Jordan., Samrah SM; Department of Internal Medicine, Respiratory and Critical Care Division, Jordan University of Science and Technology, Irbid, Jordan., Khassawneh BY; Department of Internal Medicine, Respiratory and Critical Care Division, Jordan University of Science and Technology, Irbid, Jordan., Al Ali MAK; Department of Internal Medicine, Respiratory and Critical Care Division, Jordan University of Science and Technology, Irbid, Jordan.
Jazyk: angličtina
Zdroj: Critical care research and practice [Crit Care Res Pract] 2020 Jul 30; Vol. 2020, pp. 8753764. Date of Electronic Publication: 2020 Jul 30 (Print Publication: 2020).
DOI: 10.1155/2020/8753764
Abstrakt: Background: Acute kidney injury (AKI) is a common serious problem affecting critically ill patients in intensive care unit (ICU). It increases their morbidity, mortality, length of ICU stay, and long-term risk of chronic kidney disease (CKD).
Methods: A retrospective study was carried out in a tertiary hospital in Jordan. Medical records of patients admitted to the medical ICU between 2013 and 2015 were reviewed. We aimed to identify the incidence, risk factors, and outcomes of AKI. Acute kidney injury network (AKIN) classification was used to define and stage AKI.
Results: 2530 patients were admitted to medical ICU, and the incidence of AKI was 31.6%, mainly in stage 1 (59.4%). In multivariate analysis, increasing age (odds ratio (OR) = 1.2 (95% CI 1.1-1.3), P  = 0.0001) and higher APACHE II score (OR = 1.5 (95% CI 1.2-1.7), P  = 0.001) were predictors of AKI, with 20.4% of patients started on hemodialysis. At the time of discharge, 58% of patients with AKI died compared to 51.3% of patients without AKI ( P  = 0.05). 88% of patients with AKIN 3 died by the time of discharge compared to patients with AKIN 2 and 1 (75.3% and 61.2% respectively, P  = 0.001).
Conclusion: AKI is common in ICU patients, and it increases mortality and morbidity. Close attention for earlier detection and addressing risk factors for AKI is needed to decrease incidence, complications, and mortality.
Competing Interests: The authors declare that they have no conflicts of interest.
(Copyright © 2020 Ashraf O. Oweis et al.)
Databáze: MEDLINE
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