Autor: |
Al-Fakeh MS; Department of Chemistry, College of Science, Qassim University, Buraidah 51452, Saudi Arabia.; Taiz University, Taiz 3086, Republic of Yemen., Osman SOM; Department of Physics, College of Science, Ibb University, Ibb 009674, Yemen.; Engineer College, Aljanad University for Science & Technology, Taiz 009674, Yemen., Gassoumi M; Department of Physics, College of Science, Qassim University, P.O. 64, Buraidah 51452, Saudi Arabia.; Unite de Recherche Matériaux Advances et Nanotechnologies, Institut Supérieur des Sciences Appliquées et de Technologie de Kasserine, Université de Kairouan, BP 471, 1200 Kasserine, Tunisia., Rabhi M; Department of Plant Production and Protection, College of Agriculture and Veterinary Medicine, Qassim University, Qassim 51452, Saudi Arabia., Omer M; Department of Radiologic Science, College of Applied Medical Sciences, Buraidah 51452, Saudi Arabia. |
Abstrakt: |
Due to their unique physicochemical characteristics, palladium nanoparticles (Pd-NPs) have shown tremendous promise in biological applications. The biosynthesis of Pd-NPs employing Saudi propolis has been designed to be environmental, fast, controlled, and cost-effective. The formation and stability of biosynthesized Pd-NPs by Saudi propolis extract were proved by ultraviolet-visible spectrophotometry (UV-Vis), Fourier-transform infrared spectroscopy (FT-IR), and Zeta potential analysis. Transmission electron microscopy (TEM), scanning electron microscopy (SEM), and X-ray diffraction (XRD) findings show that the average particle size of Pd-NPs is between 3.14 and 4.62 nm, which is in quantum scale. The Saudi propolis enhanced the antimicrobial activity against B. subtilis , S. aureus , E. coli , K. pneumoniae , and C. albicans . Pd-NPs show effective anticancer activity against ductal carcinoma (MCF-7) with IC50 of 104.79 µg/mL. |