| Autor: |
Kozak R; Sunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Armstrong SM; Sunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Salvant E; Sunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Ritzker C; Sunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada., Feld J; Toronto Centre for Liver Disease, University Health Network, Toronto, ON M5G 2C4, Canada., Biondi MJ; Toronto Centre for Liver Disease, University Health Network, Toronto, ON M5G 2C4, Canada., Tsui H; Sunnybrook Health Sciences Centre, Biological Science Platform, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada. |
| Abstrakt: |
A proportion of patients with COVID-19 have symptoms past the acute disease phase, which may affect quality of life. It is important for clinicians to be aware of this "long-COVID-19" syndrome to better diagnose, treat, and prevent it. We reviewed clinical and laboratory characteristics of a COVID-19 cohort in a Toronto, Ontario tertiary care center. Demographic, clinical, and laboratory data were collected, and patients were classified as "long-COVID-19" or "non-long-COVID-19" using consensus criteria. Of 397 patients who tested positive for COVID-19, 223 met inclusion criteria, and 62 (27%) had long-COVID-19. These patients had a similar age distribution compared to non-long-COVID-19 patients overall but were younger in the admitted long COVID-19 group. The long-COVID-19 group had more inpatients compared to the non-long-COVID-19 group (39% vs. 25%) and more frequent supplemental oxygen or mechanical ventilation use. However, long-COVID-19 patients did not differ by duration of mechanical ventilation, length of stay, comorbidities, or values of common laboratory tests ordered. The most frequent symptoms associated with long-COVID-19 were fatigue and weakness, as reported most commonly by the infectious disease, respirology and cardiology disciplines. In conclusion, by retrospective chart review, 27% of COVID-19 patients presenting to a tertiary care center in Toronto, Canada, were found to meet criteria for long-COVID-19. Past medical history and routine laboratory testing at presentation did not predict for long-COVID-19 development. |
