| Autor: |
Amato JN; Department of Pharmaceutical Sciences, Universidade Federal de São Paulo (UNIFESP), Diadema 09913-030, Brazil., Castelo PM; Department of Pharmaceutical Sciences, Universidade Federal de São Paulo (UNIFESP), Diadema 09913-030, Brazil., Cirino FMSB; Diadema Municipal Health Department, Diadema 09911-160, Brazil., Meyer G; Diadema Municipal Health Department, Diadema 09911-160, Brazil., Pereira LJ; Department of Health Sciences, Universidade Federal de Lavras (UFLA), Lavras 37200-900, Brazil., Sartori LC; Diadema Municipal Health Department, Diadema 09911-160, Brazil., Aderaldo NS; Department of Pharmaceutical Sciences, Universidade Federal de São Paulo (UNIFESP), Diadema 09913-030, Brazil., Silva FCE; Department of Medical and Health Sciences, School of Health and Human Development, University of Évora, 7000-671 Évora, Portugal. |
| Abstrakt: |
Background and Objectives: The aim of this retrospective cohort study was to search individual, sociodemographic and environmental predictors of COVID-19 outcomes. Materials and Methods: A convenience sample of 1036 COVID-19 confirmed patients (3-99 years, mean 59 years; 482 females) who sought treatment at the emergency units of the public health system of Diadema (Brazil; March-October 2020) was included. Primary data were collected from medical records: sex, age, occupation/education, onset of symptoms, presence of chronic diseases/treatment and outcome (death and non-death). Secondary socioeconomic and environmental data were provided by the Department of Health. Results: The mean time spent between COVID-19 symptom onset and admission to the health system was 7.4 days. Principal component analysis summarized secondary sociodemographic data, and a Poisson regression model showed that the time between symptom onset and health system admission was higher for younger people and those from the least advantaged regions (availability of electricity, a sewage network, a water supply and garbage collection). A multiple logistic regression model showed an association of age (OR = 1.08; 1.05-1.1), diabetes (OR = 1.9; 1.1-3.4) and obesity (OR = 2.9; 1.1-7.6) with death outcome, while hypertension and sex showed no significant association. Conclusion: The identification of vulnerable groups may help the development of health strategies for the prevention and treatment of COVID-19. |
