Paracetamol and Ibuprofen in the Treatment of Fever and Acute Mild-Moderate Pain in Children: Italian Experts' Consensus Statements.

Autor: Doria M; Italian Pediatricians Federation (FIMP), 30015 Chioggia, Italy., Careddu D; Italian Pediatricians Federation (FIMP), 28100 Novara, Italy., Iorio R; Department of Translational Medical Science, University of Naples Federico II, 80131 Naples, Italy., Verrotti A; Department of Pediatrics, University of Perugia, 06100 Perugia, Italy., Chiappini E; Division of Pediatric Infectious Diseases Infective Diseases, Anna Meyer Children's University Hospital, 50100 Florence, Italy.; Department of Health Sciences, University of Florence, 50100 Florence, Italy., Barbero GM; Independent Researcher, 12100 Cuneo, Italy., Ceschin F; Italian Pediatricians Federation (FIMP), 33170 Pordenone, Italy., Dell'Era L; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 20100 Milan, Italy., Fabiano V; Department of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, 20100 Milan, Italy., Mencacci M; Independent Researcher, 06100 Perugia, Italy., Carlomagno F; Independent Researcher, 80100 Naples, Italy., Libranti M; Italian Pediatricians Federation (FIMP), 95100 Catania, Italy., Mazzone T; Independent Researcher, 00100 Rome, Italy., Vitale A; Department of Pediatrics, University of Perugia, 06100 Perugia, Italy.
Jazyk: angličtina
Zdroj: Children (Basel, Switzerland) [Children (Basel)] 2021 Sep 30; Vol. 8 (10). Date of Electronic Publication: 2021 Sep 30.
DOI: 10.3390/children8100873
Abstrakt: Fever and pain are challenging symptoms in children and adolescents and are common reasons for consultations in primary care and hospital. Paracetamol and ibuprofen are currently the only recommended drugs for treating fever in Italy, but the therapeutic approaches are discrepant in the different settings. In Italy, paracetamol and ibuprofen are the most prescribed analgesics for acute mild-moderate pain in children; however, their use is often inappropriate in that fever is over-treated and pain is under-treated. An Italian board of experts analyzed the motivations for the misalignment between daily practice and guidelines of fever and acute mild-moderate pain management of the territory and hospitals. The expert opinion consensus process underscored the appropriate use of paracetamol and ibuprofen according to clinical scenarios, patients' profiles, and the safety features of the drugs. Although patients' profiles can indicate different benefits from paracetamol or ibuprofen, critical issues of fever and acute mild-moderate pain management persist in primary care and hospitals. These expert opinion consensus statements can be an across-the-board tool to harmonize the routine practice between the territory and hospitals, especially under special conditions (at-risk for dehydration, coagulation disorder patients, etc.). It can also promote educational activity about fever and acute mild-moderate pain management to enhance the milestones already achieved by Italian pediatricians.
Databáze: MEDLINE