Screening for COVID-19 in Children Undergoing Elective Invasive Procedures.

Autor: López-Martinez B; Auxiliary Diagnostic Services, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico., Blanco-Rodríguez G; Thoracic Surgery and Endoscopy Service, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico., Parra-Ortega I; Auxiliary Diagnostic Services, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico., Ramirez-Martinez CE; Thoracic Surgery and Endoscopy Service, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico., Villasis-Keever MA; Analysis and Synthesis of the Evidence Research Unit, National Medical Center XXI Century, Instituto Mexicano del Seguro Social, Mexico City, México., Miranda-Novales MG; Analysis and Synthesis of the Evidence Research Unit, National Medical Center XXI Century, Instituto Mexicano del Seguro Social, Mexico City, México., Klünder-Klünder M; Medical Research Direction, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico., De la Rosa Zamboni D; Epidemiology Services, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico., Villa Guillen M; Medical Director, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico., Nieto-Zermeño J; Medical Director, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico., Garduño-Espinosa J; Hospital Director, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico., Zurita-Cruz JN; Facultad de Medicina, Universidad Nacional Autónoma de México, Hospital Infantil de México Federico Gómez, Mexico City, 06720, Mexico. zuritajn@hotmail.com.
Jazyk: angličtina
Zdroj: Indian journal of pediatrics [Indian J Pediatr] 2022 Jul; Vol. 89 (7), pp. 651-656. Date of Electronic Publication: 2021 Oct 22.
DOI: 10.1007/s12098-021-03959-3
Abstrakt: Objective: To report the frequency of asymptomatic infection with SARS-CoV-2 in pediatric patients undergoing invasive medical procedures in a tertiary pediatric hospital.
Methods: From June to October 2020, a SARS-CoV-2 real-time reverse-transcription polymerase chain reaction (rRT-PCR) test was performed for all pediatric patients scheduled to undergo an elective invasive procedure. None of the patients was symptomatic. The cycle threshold (Ct) values of the ORF1ab gene were recorded for all patients.
Results: A total of 700 patients were screened for SARS-CoV-2 infection. The median age was 5.7 y old. In total, 46.6% (n = 326) of the patients were male, and 53.4% (n = 374) were female. The most common underlying diseases were hemato-oncological (25.3%), gastrointestinal (24.9%), and genitourinary (10.3%). The main scheduled surgical-medical procedures were surgical treatment for acquired congenital diseases, biopsy sampling, local therapy administration, organ transplantation, and the placement of central venous catheters, among others. The SARS-CoV-2 rRT-PCR test was positive in 9.4% (66), and the median Ct value was 35.8. None of the patients developed COVID-19.
Conclusions: The frequency of asymptomatic SARS-CoV-2 infection was detected in less than 10% of pediatric patients scheduled to undergo an elective invasive procedure in a tertiary hospital. This frequency is higher than those in reports from different countries.
(© 2021. Dr. K C Chaudhuri Foundation.)
Databáze: MEDLINE
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