Medication-related quality of life (MRQoL) in ambulatory older adults with multi-morbidity and polypharmacy.

Autor: Jennings ELM; Department of Medicine (Geriatric Medicine), University College Cork, Wilton, T12 DC4A, Cork, Ireland. elmjennings@gmail.com.; Department of Geriatric Medicine, Cork University Hospital, Wilton, Cork, Ireland. elmjennings@gmail.com., O'Mahony D; Department of Medicine (Geriatric Medicine), University College Cork, Wilton, T12 DC4A, Cork, Ireland.; Department of Geriatric Medicine, Cork University Hospital, Wilton, Cork, Ireland., Gallagher PF; Department of Medicine (Geriatric Medicine), University College Cork, Wilton, T12 DC4A, Cork, Ireland.; Department of Medicine (Geriatric Medicine), Bon Secours Hospital, Cork, Ireland.
Jazyk: angličtina
Zdroj: European geriatric medicine [Eur Geriatr Med] 2022 Jun; Vol. 13 (3), pp. 579-583. Date of Electronic Publication: 2021 Oct 21.
DOI: 10.1007/s41999-021-00573-6
Abstrakt: Purpose: To assess medication-related quality-of-life (MRQoL) in multi-morbid older adults with polypharmacy and correlations with medications, frailty and health-related QoL.
Methods: With a cross sectional study of multi-morbid geriatric medicine outpatients, we assessed MRQoL (MRQol-LSv1), frailty status, potentially inappropriate medications, Medication Adherence Rating Scale (MARS), health-related-QoL (Short-Form 12, SF12) and medication burden (Living with Medicines Questionnaire, LMQv2).
Results: One-in-four (n = 59) of 234 outpatient attendees met inclusion criteria. Almost half (n = 106, 45%) were excluded due to cognition (MMSE < 26). Included participants (n = 27, mean age 80.2 years) experienced a median of 11 (IQR 9-13.5) co-morbidities and were prescribed a median of 10 (IQR 8-12.25) medications. Overall, MRQoL-LS.v.1 scores were low, suggesting good medication-related quality of life (median MRQoL-LS.v.1 score of 14, IQR 14-22). Correlations between MRQoL, number of daily medications, co-morbidity burden, LMQv2 score, SF12 scores and number of PIMs were non-significant.
Conclusion: MRQoL-LSv.1 is unsuitable for most patients attending geriatric ambulatory services.
(© 2021. The Author(s).)
Databáze: MEDLINE
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