Molecular docking analysis of COX-2 for potential inhibitors.
| Autor: | Selvaraj J; Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India., Vishnupriya V; Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India., Sardar H; Department of Biotechnology, Government Science College, Chitradurga-577501, Karnataka, India., Balakrishna JP; Department of Stem Cell Biology, Stellixir Biotech Pvt Ltd, No.V-31, 2nd floor, 10th Main Road, Peenya 2nd Stage Industrial Area, Bangalore - 560058, Karnataka, India., Rex J; Department of Biochemistry, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India., Mohan SK; Department of Biochemistry and Department of Clinical Skills & Simulation, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India., Vijayalakshmi P; PG & Research Department of Biotechnology & Bioinformatics, Holy Cross College (Autonomous), Trichy- 620002, Tamil Nadu, India., Ponnulakshmi R; Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai-600 078, India. |
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| Jazyk: | angličtina |
| Zdroj: | Bioinformation [Bioinformation] 2020 Oct 31; Vol. 16 (10), pp. 753-758. Date of Electronic Publication: 2020 Oct 31 (Print Publication: 2020). |
| DOI: | 10.6026/97320630016753 |
| Abstrakt: | Cyclooxygenase-2 (COX-2) is liked with breast cancer. Therefore, it is of interest to design and develop new yet effective compounds against COX-2 from medicinal plants such as the natural alkaloid compounds. We document the optimal binding features of aristolochicacid with COX-2 protein for further consideration. Competing Interests: None declared (© 2020 Biomedical Informatics.) |
| Databáze: | MEDLINE |
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