| Autor: |
Khalangot M; Shupyk National Healthcare University of Ukraine, Kyiv 04112, Ukraine.; Komisarenko Institute of Endocrinology and Metabolism, Kyiv 04114, Ukraine., Sheichenko N; Infectious Diseases Hospital, Kostiantynivka 85113, Ukraine., Gurianov V; Bohomolets National Medical University, Kyiv 01601, Ukraine., Vlasenko V; Infectious Diseases Hospital, Kostiantynivka 85113, Ukraine., Kurinna Y; Shupyk National Healthcare University of Ukraine, Kyiv 04112, Ukraine., Samson O; Shupyk National Healthcare University of Ukraine, Kyiv 04112, Ukraine., Tronko M; Shupyk National Healthcare University of Ukraine, Kyiv 04112, Ukraine.; Komisarenko Institute of Endocrinology and Metabolism, Kyiv 04114, Ukraine. |
| Abstrakt: |
An observational study was conducted in Ukraine to determine the independent mortality risks among adult inpatients with COVID-19. The results of treatment of COVID-19 inpatients ( n = 367) are presented, and waist circumference (WC) was measured. Logistic regression analysis was applied to evaluate the effects of factors on the risk of mortality. Odds ratios and 95% CIs for the association were calculated. One hundred and three of 367 subjects had fasting plasma glucose level that met the diabetes mellitus criteria (≥7.0 mmol/L), in 53 patients, diabetes mellitus was previously known. Two hundred and eleven patients did not have diabetes or hyperglycemia. Diabetes mellitus/hyperglycemia odds ratio 2.5 (CI 1.0-6.1), p = 0.045 loses statistical significance after standardization by age, waist circumference or fasting plasma glucose. No effect on gender, body mass index-determined obesity, or hypertension was found. The fasting plasma glucose (>8.5 mmol/L), age (≥61 years), and waist circumference (>105 cm) categories were associated with ORs 6.34 (CI 2.60-15.4); 4.12 (CI 1.37-12.4); 8.93 (CI 3.26-24.5), respectively. The optimal model of mortality risk with AUC 0.86 (CI 0.81-0.91) included the diabetes/heperglycemia and age categories as well as waist circumference as a continued variable. Waist circumference is an independent risk factor for mortality of inpatients with COVID-19. |
