Effect of hyperbaric oxygen therapy and Tomatis sound therapy in children with autism spectrum disorder.

Autor: El-Tellawy MM; Departments of Pediatrics, College of Medicine, Jouf University, Sakaka, Saudi Arabia; Departments of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt., Ahmad AR; Departments of Pediatrics, College of Medicine, Jouf University, Sakaka, Saudi Arabia; Departments of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt., Saad K; Departments of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt; Department of Pediatrics, Faculty of Medicine, Alrayan Colleges, Madinah, Saudi Arabia. Electronic address: khaled.ali@med.au.edu.eg., Alruwaili TAM; Departments of Pediatrics, College of Medicine, Jouf University, Sakaka, Saudi Arabia., AbdelMoneim IM; Department of Psychology, Speech, and Special Needs, Faculty of Arts, Assiut University, Assiut, Egypt., Shaaban I; Department of Neuropsychiatry, Faculty of Medicine, Azhar University, Egypt., Alinad AKM; College of Medicine, Jouf University, Sakaka, Saudi Arabia., Albulayhid SBH; College of Medicine, Jouf University, Sakaka, Saudi Arabia., Khalaf SM; Departments of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
Jazyk: angličtina
Zdroj: Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2022 Mar 08; Vol. 113, pp. 110457. Date of Electronic Publication: 2021 Oct 16.
DOI: 10.1016/j.pnpbp.2021.110457
Abstrakt: Many therapeutic and dietary regimens have been studied for children with autism spectrum disorder (ASD) in the last three decades. We aimed to evaluate the efficacy of hyperbaric oxygen therapy (HBOT) and Tomatis sound therapy (TST) in an Egyptian cohort of children with ASD. This study was a prospective, open label, randomized interventional clinical trial. One hundred forty-six children with ASD with no previous rehabilitation therapy were enrolled in our study. Patients were randomly divided into four groups: the first group received hyperbaric oxygen therapy, the second group received Tomatis sound therapy, the third group received a combination of both modalities, and the fourth group, the control group, received no intervention. We found that the combination of Tomatis sound therapy with hyperbaric oxygen therapy had a superior effect in improving autism symptoms than each intervention alone (CARS after therapy 35.04 ± 13.38 versus 49.34 ± 17.54 before the intervention, p < 0.001). The combination of both modalities may be helpful for children with ASD. The most distinctive evidence that supports the use of combination therapy for ASD is still controversial; however, our study provides some evidence of the benefit of combination therapy for children with ASD. Future studies should use a more sophisticated research design and begin by finding a consistent baseline measure that can be used to evaluate the effects of these therapies for ASD.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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