Cutaneous manifestation of polycystic ovary syndrome.

Autor: Abusailik MA; Department of Dermatology, Jordanian Royal Medical Services, Amman., Muhanna AM; Department of Dermatology, Jordanian Royal Medical Services, Amman., Almuhisen AA; Department of Dermatology, Jordanian Royal Medical Services, Amman., Alhasanat AM; Department of Dermatology, Jordanian Royal Medical Services, Amman., Alshamaseen AM; Department of Obstetrics and Gynecology, Jordanian Royal Medical Services, Amman., Bani Mustafa SM; Department of Dermatology, Jordanian Royal Medical Services, Amman., Nawaiseh MB; Jordanian Royal Medical Services, Amman, Jordan.
Jazyk: angličtina
Zdroj: Dermatology reports [Dermatol Reports] 2021 Sep 15; Vol. 13 (2), pp. 8799. Date of Electronic Publication: 2021 Sep 15 (Print Publication: 2021).
DOI: 10.4081/dr.2021.8799
Abstrakt: The aim of this cross-sectional study, that included 146 polycystic ovary syndrome (PCOS) patients, was to evaluate the prevalence, severity and pattern of cutaneous manifestation in Jordanian women with PCOS, as well as their correlation with hormonal abnormalities. A thorough complete cutaneous examination, hormonal assays (Luteinizing hormone [LH], follicle stimulating hormone [FSH], prolactin, total testosterone, free testosterone, dehydroepiandrosterone sulfate) and pelvic ultrasonography were done. The most common cutaneous features of PCOS were acne vulgaris (75.3%) followed by hirsutism (59.6%) then seborrhea (43.2%) and androgenetic alopecia (42.5%). Patients who had acne vulgaris presented at a younger age than patients who did not. Patients who had androgenetic alopecia and stria were older than patients with no such features. Moreover, all cutaneous manifestations of PCOS, except for acne, were associated with higher body mass index (BMI). Elevated LH:FSH ratio of more than 2:1 was the most common hormonal abnormality, followed by increased LH and total testosterone. Acne, hirsutism, androgenetic alopecia, seborrhea, acanthosis nigricans and skin tags are common cutaneous manifestations among Jordanian patients with PCOS. The existence of one or more of these features, especially in overweight and obese patients, should alert the physician towards the possibility of having PCOS.
Competing Interests: Conflict of interest: The authors declare no potential conflict of interest.
(©Copyright: the Author(s).)
Databáze: MEDLINE