| Autor: |
Hsu YH; Department of Psychology, National Chung Cheng University, Chiayi, Taiwan.; Center for Innovative Research on Aging Society (CIRAS), National Chung Cheng University, Chiayi, Taiwan., Lee M; Department of Neurology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Division of Cardiology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Pan KL; Division of Cardiology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; School of Medicine, Chang Gung University, Taoyuan, Taiwan.; Heart Failure Center, Chang Gung Memorial Hospital, Chiayi, Taiwan., Chen CY; Department of Psychology, National Chung Cheng University, Chiayi, Taiwan., Hung TH; School of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Psychiatry, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.; Chang Gung Institute of Technology, Taoyuan, Taiwan., Chen VC; School of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Psychiatry, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan. |
| Abstrakt: |
Hypertension has been associated with risk of cognitive impairments. The American Heart Association recommended the use of the harmonized neuropsychological protocol suggested by the National Institute of Neurologic Disorders and Stroke and the Canadian Stroke Network (NINDS-CSN) for studying related cognitive impairments. Initially designed for vascular cognitive impairment, empirical data of results from NINDS-CSN protocol has not been well-established in hypertension. The present study recruited 58 adults diagnosed with hypertension and 44 normotensive controls. Tests from the NINDS-CSN protocol were given in three lengths, including neuropsychological tests and neuropsychiatric inventories. The results showed higher proportions of hypertensive adults with impairments on tests of memory and executive functions and that they performed worse as a group on several tests from the 30-minute protocol, but not on the other additional tests in the full-length version, nor on cognitive screening test in the 5-minute protocol such as the Mini-Mental State Examination or the Montreal Cognitive Assessment. There was no significant group difference on neuropsychiatric symptoms. These findings suggested that the 30-minute version of the NINDS-CSN protocol with the two supplemental tests was able to reveal selective cognitive deficits in hypertensive adults and provide a practical solution for related studies, balancing between the requirement of sensitivity, domain variety, and brevity. |
