Perception and knowledge of pharmacogenetics among Brazilian psychiatrists.

Autor: Almeida BC; Jundiaí Medical School (FMJ), Jundiaí, SP, Brazil., Gonçalves ED; Jundiaí Medical School (FMJ), Jundiaí, SP, Brazil., de Sousa MH; Department of Public Health, Jundiaí Medical School (FMJ), Jundiaí, SP, Brazil., Osis MJMD; Department of Public Health, Jundiaí Medical School (FMJ), Jundiaí, SP, Brazil; Department of Tocogynecology, University of Campinas CAISM/UNICAMP, Campinas, SP, Brazil., de Brito Mota MJB; Department of Public Health, Jundiaí Medical School (FMJ), Jundiaí, SP, Brazil; Department of Dentistry, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, SP, Brazil., Planello AC; Department of Morphology and Pathology, Jundiaí Medical School (FMJ), Jundiaí, SP, Brazil; Department of Bioscience, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, SP, Brazil. Electronic address: alineplanello@g.fmj.br.
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 2021 Dec; Vol. 306, pp. 114238. Date of Electronic Publication: 2021 Oct 11.
DOI: 10.1016/j.psychres.2021.114238
Abstrakt: Pharmacogenetics (PGx) can optimize drug therapy in psychiatry and is particularly important in admixed populations. Here we developed and successfully validated a questionnaire for assessing the perception and knowledge of PGx among Brazilian psychiatrists. Overall, the participants showed some familiarity with PGx. Most psychiatrists reported to have knowledge of PGx and recognized its usefulness in psychiatry; however, they declared concerns regarding PGx education, the request of tests and their interpretation, cost-effectiveness, and ethical issues. PGx testing is relatively prevalent in their clinical practice, but education on the topic is lacking. Bivariate analysis revealed significant associations. Psychiatrists > 40 years of age more frequently had a positive perception of other clinicians' familiarity with PGx. Psychiatrists in private health services showed less self-reported competency in the use of PGx testing. Furthermore, women had better perception of PGx education. The present study adds knowledge about PGx in psychiatry and encourages the development of educational and training resources for PGx to improve its clinical implementation.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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