Task-evoked simultaneous FDG-PET and fMRI data for measurement of neural metabolism in the human visual cortex.

Autor:	Jamadar SD; Monash Biomedical Imaging, Monash University, Melbourne, VIC, Australia. sharna.jamadar@monash.edu.; Australian Research Council Centre of Excellence for Integrative Brain Function, Clayton, Australia. sharna.jamadar@monash.edu.; Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC, Australia. sharna.jamadar@monash.edu., Zhong S; Monash Biomedical Imaging, Monash University, Melbourne, VIC, Australia.; National Imaging Facility, Clayton, Australia., Carey A; Monash Biomedical Imaging, Monash University, Melbourne, VIC, Australia.; Department of Medical Imaging, Monash Health, Clayton, VIC, Australia., McIntyre R; Monash Biomedical Imaging, Monash University, Melbourne, VIC, Australia.; Department of Medical Imaging, Monash Health, Clayton, VIC, Australia., Ward PGD; Monash Biomedical Imaging, Monash University, Melbourne, VIC, Australia.; Australian Research Council Centre of Excellence for Integrative Brain Function, Clayton, Australia.; Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC, Australia., Fornito A; Australian Research Council Centre of Excellence for Integrative Brain Function, Clayton, Australia.; Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC, Australia., Premaratne M; Department of Electrical and Computer Systems Engineering, Monash University, Clayton, VIC, Australia., Jon Shah N; Institute of Neuroscience and Medicine - 4, Forschungszentrum Jülich, Jülich, Germany., O'Brien K; MR Research Collaborations, Siemens Healthcare Pty Ltd, Clayton, Australia., Stäb D; MR Research Collaborations, Siemens Healthcare Pty Ltd, Clayton, Australia., Chen Z; Monash Biomedical Imaging, Monash University, Melbourne, VIC, Australia.; Monash Data Futures Institute, Monash University, Clayton, Australia., Egan GF; Monash Biomedical Imaging, Monash University, Melbourne, VIC, Australia.; Australian Research Council Centre of Excellence for Integrative Brain Function, Clayton, Australia.; Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC, Australia.
Jazyk:	angličtina
Zdroj:	Scientific data [Sci Data] 2021 Oct 15; Vol. 8 (1), pp. 267. Date of Electronic Publication: 2021 Oct 15.
DOI:	10.1038/s41597-021-01042-2
Abstrakt:	Understanding how the living human brain functions requires sophisticated in vivo neuroimaging technologies to characterise the complexity of neuroanatomy, neural function, and brain metabolism. Fluorodeoxyglucose positron emission tomography (FDG-PET) studies of human brain function have historically been limited in their capacity to measure dynamic neural activity. Simultaneous [18 F]-FDG-PET and functional magnetic resonance imaging (fMRI) with FDG infusion protocols enable examination of dynamic changes in cerebral glucose metabolism simultaneously with dynamic changes in blood oxygenation. The Monash vis-fPET-fMRI dataset is a simultaneously acquired FDG-fPET/BOLD-fMRI dataset acquired from n = 10 healthy adults (18-49 yrs) whilst they viewed a flickering checkerboard task. The dataset contains both raw (unprocessed) images and source data organized according to the BIDS specification. The source data includes PET listmode, normalization, sinogram and physiology data. Here, the technical feasibility of using opensource frameworks to reconstruct the PET listmode data is demonstrated. The dataset has significant re-use value for the development of new processing pipelines, signal optimisation methods, and to formulate new hypotheses concerning the relationship between neuronal glucose uptake and cerebral haemodynamics. (© 2021. The Author(s).)
Databáze:	MEDLINE
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