Prevalence of autoimmune conditions in pregnant women in a tertiary maternity hospital: A cross-sectional survey and maternity database review.

Autor:	Lim JR; Sydney Medical School, The University of Sydney, Sydney, Australia., Nielsen TC; Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Dale RC; Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Jones HF; Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Beech A; Department of Endocrinology/Obstetric Medicine, Royal Hospital for Women, Sydney, Australia., Nassar N; Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Lain SJ; Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Shand A; Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.; Department of Maternal Fetal Medicine, Royal Hospital for Women, Sydney, Australia.
Jazyk:	angličtina
Zdroj:	Obstetric medicine [Obstet Med] 2021 Sep; Vol. 14 (3), pp. 158-163. Date of Electronic Publication: 2020 Nov 03.
DOI:	10.1177/1753495X20964680
Abstrakt:	Background: Autoimmune conditions are associated with adverse pregnancy and offspring outcomes; however, the prevalence in pregnant women is not well understood. Estimates based on administrative data alone may underestimate prevalence. Methods: A cross-sectional survey of women attending a tertiary referral hospital for antenatal care in December 2018-February 2019 and review of the hospital's maternity database of women giving birth from October 2017-June 2018 to estimate autoimmune disease prevalence. Results: A total of 400 women completed surveys (78% response rate) and 41 (10.3%) reported an autoimmune disease, most commonly Hashimoto's thyroiditis (2.8%) and psoriasis (2.5%). From the maternity database, 112 of 2756 women giving birth (4.1%) had a recorded autoimmune disease, most commonly Hashimoto's thyroiditis (1.3%) followed by coeliac disease, Graves' disease, and immune thrombocytopenic purpura (all 0.4%). Conclusion: Autoimmune disease prevalence in pregnant women is higher when self-reported and may be more common than previously reported using administrative data. (© The Author(s) 2020.)
Databáze:	MEDLINE
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