Using discrete choice experiment to investigate patients' and parents' preferences for initiating ADHD medication.

Autor: Khan MU; The University of Sydney School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia., Balbontin C; Institute of Transport and Logistics Studies, The University of Sydney Business School, The University of Sydney, Camperdown, NSW, Australia., Bliemer M; Institute of Transport and Logistics Studies, The University of Sydney Business School, The University of Sydney, Camperdown, NSW, Australia., Aslani P; The University of Sydney School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.
Jazyk: angličtina
Zdroj: Journal of mental health (Abingdon, England) [J Ment Health] 2023 Apr; Vol. 32 (2), pp. 373-385. Date of Electronic Publication: 2021 Oct 10.
DOI: 10.1080/09638237.2021.1979495
Abstrakt: Background: The decision to initiate medication is complex and is influenced by a variety of factors. There is limited information on the relative importance of factors that influence the initiation of ADHD medication.
Aims: To investigate the factors, and their relative importance, that influence the decision to initiate medication in adults, and parents of children, with ADHD.
Methods: A discrete choice experiment was conducted using eight choice tasks made up of five attributes that described the outcomes of initiating medication. A mixed multinomial logit model was used to estimate preferences for medication.
Results: Respondents' overall preferences for initiating medication were negative (Mean (β)= -0.72705, p  < 0.1), however, significant heterogeneity was noted in preferences (SD: 0.93604, p  < 0.001). Side-effects were the most important factor for both adults (Relative importance (RI) = 40.39%) and parents (RI = 41.99%). Improvement in education had a greater weighting in adults' decision-making compared to parents (RI = 36.93% vs 30.47%) while improvement in aggressive (RI = 14.38% vs 11.84%) and social behaviour (RI = 12.59% vs 10.37%) was more important to parents.
Conclusions: Important differences in preferences of patients and parents were identified, highlighting that the decision to initiate medication is influenced differently in different individuals and groups.
Databáze: MEDLINE
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