Recent trends in nanomaterial-based signal amplification in electrochemical aptasensors.

Autor: Kurup CP; Biosensors and Nanobiotechnology Laboratory, Integrated Science Building, Faculty of Science, Universiti Brunei Darussalam, Gadong, Brunei Darussalam., Mohd-Naim NF; Biosensors and Nanobiotechnology Laboratory, Integrated Science Building, Faculty of Science, Universiti Brunei Darussalam, Gadong, Brunei Darussalam.; PAPRSB Institute of Health Science, Universiti Brunei Darussalam, Gadong, Brunei Darussalam., Ahmed MU; Biosensors and Nanobiotechnology Laboratory, Integrated Science Building, Faculty of Science, Universiti Brunei Darussalam, Gadong, Brunei Darussalam.
Jazyk: angličtina
Zdroj: Critical reviews in biotechnology [Crit Rev Biotechnol] 2022 Aug; Vol. 42 (5), pp. 794-812. Date of Electronic Publication: 2021 Oct 10.
DOI: 10.1080/07388551.2021.1960792
Abstrakt: Ultrasensitive biosensors have become a necessity in the world of scientific research, and several signal enhancement strategies have been employed to attain exceptionally low detection limits. Nanotechnology turns out to be a strong contender for signal amplification, as they can be employed as platform modifiers, catalysts, carriers or labels. Here, we have described the most recent advancements in the utilization of nanomaterials as signal amplification components in aptamer-based electrochemical biosensors. We have briefly reviewed the methods that utilized nanomaterials, namely gold and carbon, as well as nanocomposites such as: graphene, carbon nanotubes, quantum dots, and metal-organic frameworks.
Databáze: MEDLINE
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