The epidemiology and management of odontogenic keratocysts (OKCs): A European multicenter study.

Autor: Boffano P; Division of Dentistry, Vercelli Hospital, Vercelli, Italy. Electronic address: paolo.boffano@gmail.com., Cavarra F; Division of Dentistry, Vercelli Hospital, Vercelli, Italy., Agnone AM; Division of Dentistry, Vercelli Hospital, Vercelli, Italy., Brucoli M; Division of Maxillofacial Surgery, University Hospital 'Maggiore Della Carità', University of Eastern Piedmont, Novara, Italy., Ruslin M; Department of Oral and Maxillofacial Surgery, Hasanuddin University, Makassar, Indonesia., Forouzanfar T; Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center, Amsterdam, the Netherlands., Ridwan-Pramana A; Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center, Amsterdam, the Netherlands., Rodríguez-Santamarta T; Servicio de Cirugía Maxilofacial, Hospital Universitario Central de Asturias, Oviedo, Spain., de Vicente JC; Servicio de Cirugía Maxilofacial, Hospital Universitario Central de Asturias, Oviedo, Spain., Starch-Jensen T; Department of Oral and Maxillofacial Surgery, Aalborg University Hospital, Aalborg, Denmark., Pechalova P; Department of Oral Surgery, Medical University of Plovdiv, Bulgaria., Pavlov N; Clinic of Maxillofacial Surgery, University Hospital 'St. George', Plovdiv, Bulgaria., Doykova I; Department of Maxillofacial Surgery, Medical University of Plovdiv, Bulgaria., Gospodinov D; Department of Oral Surgery, Medical University of Plovdiv, Bulgaria., Konstantinovic VS; School of Dental Medicine, University of Belgrade, Belgrade, Serbia., Jovanović M; School of Dental Medicine, University of Belgrade, Belgrade, Serbia., Barrabé A; Department of Oral and Maxillofacial Surgery - Hospital Dentistry Unit, University Hospital of Besançon - France., Louvrier A; Department of Oral and Maxillofacial Surgery - Hospital Dentistry Unit, University Hospital of Besançon - France; University of Franche-Comté, INSERM, EFS BFC, UMR 1098 Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, F-25000 Besançon - France., Meyer C; Department of Oral and Maxillofacial Surgery - Hospital Dentistry Unit, University Hospital of Besançon - France; University of Franche-Comté, EA 4662 Nanomedicine Lab Imagery and Therapeutics, F-25000 Besançon - France., Tamme T; Department of Stomatology, University of Tartu, Estonia., Andrianov A; Department of Stomatology, University of Tartu, Estonia., Dovšak T; Department of Maxillofacial and Oral Surgery of the University Medical Centre, Ljubljana, Slovenia., Birk A; Department of Maxillofacial and Oral Surgery of the University Medical Centre, Ljubljana, Slovenia., Masu L; Division of Pathology, Vercelli Hospital, Vercelli, Italy., Rocchetti V; Division of Dentistry, Vercelli Hospital, Vercelli, Italy.
Jazyk: angličtina
Zdroj: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery [J Craniomaxillofac Surg] 2022 Jan; Vol. 50 (1), pp. 1-6. Date of Electronic Publication: 2021 Oct 04.
DOI: 10.1016/j.jcms.2021.09.022
Abstrakt: The objective of the present study was to assess the epidemiology including demographic variables, diagnostic features, and the management of odontogenic keratocyst (OKCs) at several European departments of maxillofacial and oral surgery. This study is based on a systematic computer-assisted database that allowed the recording of data from treated OKCs. The following data were recorded for each patient: gender, age, voluptuary habits, comorbidities, site, size, radiographic features, treatment of OKCs, length of hospital stay, complications, recurrence, management and complications of eventual recurrence. A total of 405 patients, 249 male and 156 female, with 415 OKCs (407 sporadic and 8 syndromic lesions) were included in the study: 320 lesions were found in the mandible, whereas 95 were found in the maxilla. In the mandible, the most frequently involved subsite was the angle, whereas in the maxilla it was the molar region. The most frequently performed treatment option was enucleation plus curettage/peripheral ostectomy in 204 OKCs (recurrence rate, 9%). Decompression without residual cystectomy (recurrence rate, 66%), marsupialization with residual enucleation with the use of Carnoy's solution (recurrence rate, 50%), decompression with residual cystectomy (recurrence rate, 43%), and simple enucleation (recurrence rate, 24%) were the treatment options with the highest recurrence rates. An appropriate management of odontogenic keratocysts should be individualized, taking into consideration clinical and radiological findings, as well as patients' age and comorbidities.
Competing Interests: Declaration of competing interest None of the authors listed have any conflicts of interest to report. None of the authors have a financial interest in any of the products, devices, or drugs mentioned in this manuscript.
(Copyright © 2021 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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