| Autor: |
Stuart T; Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721, USA., Kasper KA; Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721, USA., Iwerunmor IC; Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ 85721, USA., McGuire DT; Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721, USA., Peralta R; Department of Aerospace and Mechanical Engineering, University of Arizona, Tucson, AZ 85721, USA., Hanna J; Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721, USA., Johnson M; Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721, USA., Farley M; Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721, USA., LaMantia T; Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721, USA., Udorvich P; Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ 85721, USA., Gutruf P; Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721, USA.; Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ 85721, USA.; Bio5 Institute, University of Arizona, Tucson, AZ 85721, USA.; Neroscience GIDP, University of Arizona, Tucson, AZ 85721, USA. |
| Abstrakt: |
Digital medicine, the ability to stream continuous information from the body to gain insight into health status, manage disease, and predict onset health problems, is only gradually developing. Key technological hurdles that slow the proliferation of this approach are means by which clinical grade biosignals are continuously obtained without frequent user interaction. To overcome these hurdles, solutions in power supply and interface strategies that maintain high-fidelity readouts chronically are critical. This work introduces a previously unexplored class of devices that overcomes the limitations using digital manufacturing to tailor geometry, mechanics, electromagnetics, electronics, and fluidics to create unique personalized devices optimized to the wearer. These elastomeric, three-dimensional printed, and laser-structured constructs, called biosymbiotic devices, enable adhesive-free interfaces and the inclusion of high-performance, far-field energy harvesting to facilitate continuous wireless and battery-free operation of multimodal and multidevice, high-fidelity biosensing in an at-home setting without user interaction. |
