| Autor: |
Cardoso RR; Department of Food Technology, Federal University of Vicosa, Vicosa-MG, Brazil. fredbarros@ufv.br., Moreira LPD; Department of Nutrition and Health, Federal University of Vicosa, Vicosa-MG, Brazil., de Campos Costa MA; Department of Food Technology, Federal University of Vicosa, Vicosa-MG, Brazil. fredbarros@ufv.br., Toledo RCL; Department of Nutrition and Health, Federal University of Vicosa, Vicosa-MG, Brazil., Grancieri M; Department of Nutrition and Health, Federal University of Vicosa, Vicosa-MG, Brazil., Nascimento TPD; Laboratory of Bioactives, Food and Nutrition Graduate Program, Federal University of the State of Rio de Janeiro (UNIRIO), Rio de Janeiro, Brazil., Ferreira MSL; Laboratory of Bioactives, Food and Nutrition Graduate Program, Federal University of the State of Rio de Janeiro (UNIRIO), Rio de Janeiro, Brazil.; Laboratory of Protein Biochemistry, Center for Innovation in Mass Spectrometry, UNIRIO, Rio de Janeiro, Brazil., da Matta SLP; Department of General Biology, Federal University of Vicosa, Vicosa-MG, Brazil., Eller MR; Department of Food Technology, Federal University of Vicosa, Vicosa-MG, Brazil. fredbarros@ufv.br., Duarte Martino HS; Department of Nutrition and Health, Federal University of Vicosa, Vicosa-MG, Brazil., de Barros FAR; Department of Food Technology, Federal University of Vicosa, Vicosa-MG, Brazil. fredbarros@ufv.br. |
| Abstrakt: |
The aim of this study was to evaluate the effect of green and black tea kombuchas consumption on adiposity, lipid and glucose metabolism, liver steatosis, oxidative stress, and inflammation in Wistar rats fed a high-fat high-fructose (HFHF) diet. Wistar rats, after 8 weeks to induce metabolic alterations, were divided into an AIN-93M control group, HFHF control group, green tea kombucha + HFHF diet (GTK group), and black tea kombucha + HFHF diet (BTK group), for 10 weeks. The kombuchas improved glucose metabolism, plasma total antioxidant capacity, superoxide dismutase activity, and decreased nitric oxide concentration. Moreover, both kombuchas reduced systemic inflammation by decreasing the neutrophil/lymphocyte ratio (NLR), reduced the total adipose tissue and blood triglyceride, and reverted liver steatosis (from grade 2 to 1), besides the modulation of genes related to adipogenesis and β-oxidation. Therefore, kombuchas from green and black teas have bioactive properties that can help control metabolic alterations induced by the HFHF diet. |
