Mild Cognitive Impairment or Attention-Deficit/Hyperactivity Disorder in Older Adults? A Cross Sectional Study.

Autor:	Mendonca F; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Sudo FK; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Santiago-Bravo G; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Oliveira N; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Assuncao N; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Rodrigues F; Department of Speech and Hearing Pathology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Soares R; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Calil V; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Bernardes G; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Erthal P; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Drummond C; Department of Speech and Hearing Pathology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Tovar-Moll F; D'Or Institute For Research and Education, Rio de Janeiro, Brazil., Mattos P; D'Or Institute For Research and Education, Rio de Janeiro, Brazil.; Department of Psychiatry and Forensic Medicine, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Jazyk:	angličtina
Zdroj:	Frontiers in psychiatry [Front Psychiatry] 2021 Sep 20; Vol. 12, pp. 737357. Date of Electronic Publication: 2021 Sep 20 (Print Publication: 2021).
DOI:	10.3389/fpsyt.2021.737357
Abstrakt:	Background: Attention-Deficit/Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental condition, which may be associated with life-enduring cognitive dysfunction. It has been hypothesized that age-related cognitive decline may overlap with preexisting deficits in older ADHD patients, leading to increased problems to manage everyday-life activities. This phenomenon may mimic neurodegenerative disorders, in particular Mild Cognitive Impairment (MCI). This cross-sectional study aims to assess cognitive and behavioral differences between older subjects with ADHD and MCI. Methods: A total of 107 older participants (41 controls; 40 MCI and 26 ADHD; mean age = 67.60 ± 7.50 years; mean schooling = 15.14 ± 2.77 years; 65.4% females) underwent clinical, cognitive, and behavioral assessments by a multidisciplinary team at the Memory Clinic, D'Or Institute for Research and Education, Rio de Janeiro, Brazil. Mean scores in neuropsychological tasks and behavioral scales were compared across groups. Results: Participants with ADHD showed poorer performances than controls in episodic memory and executive function with large effect-sizes. Performances were comparable between MCI and ADHD for all domains. Discussion: MCI and ADHD in older individuals are dissociated clinical entities with overlapping cognitive profiles. Clinicians ought to be aware of these converging phenotypes to avoid misdiagnosis. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2021 Mendonca, Sudo, Santiago-Bravo, Oliveira, Assuncao, Rodrigues, Soares, Calil, Bernardes, Erthal, Drummond, Tovar-Moll and Mattos.)
Databáze:	MEDLINE
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