Auditory event-related electroencephalographic potentials in borderline personality disorder.

Autor: Penengo C; Unit of Psychiatry, Department of Medicine (DAME), University of Udine, Udine, Italy., Colli C; Unit of Psychiatry, Department of Medicine (DAME), University of Udine, Udine, Italy., Bonivento C; IRCCS 'E. Medea', Polo Friuli Venezia Giulia, San Vito al Tagliamento (PN), Italy., Boscutti A; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Balestrieri M; Unit of Psychiatry, Department of Medicine (DAME), University of Udine, Udine, Italy., Delvecchio G; Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Brambilla P; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Jazyk: angličtina
Zdroj: Journal of affective disorders [J Affect Disord] 2022 Jan 01; Vol. 296, pp. 454-464. Date of Electronic Publication: 2021 Oct 01.
DOI: 10.1016/j.jad.2021.09.096
Abstrakt: Background: Borderline Personality Disorder (BPD) is characterized by mood dysregulation, impulsivity, identity disturbances, and a higher risk for suicide. Currently, the diagnosis is solely based on clinical observation of overt symptoms, and this can delay the detection of the disease and the timely start of appropriate treatment. Several candidate clinical tools have been studied to better characterize BPD, including event-related potentials (ERP). This review aimed at summarizing the results of the available ERP studies on BPD to clarify the possible application of this technique in the early diagnosis of BPD.
Methods: A bibliographic search on PubMed and PsycInfo was performed in order to identify studies comprising individuals with BPD diagnosis and a control group that evaluated the ERP elicited by auditory stimuli.
Results: Ten studies that explored various ERP components associated with auditory stimuli in BPD were included. Overall, the results showed that positive ERP (P50, P100, and P300) amplitude and latencies as well as loudness dependance were altered in BPD patients compared to controls, possibly reflecting deficits involving attention, mainly at its early stage, and executive functions.
Limitations: The reviewed studies used different ERP approaches and non-homogeneous BPD diagnostic criteria.
Conclusions: Auditory ERP appear to be a promising tool for the assessment of BPD patients, especially for early diagnosis and evaluation of cognitive symptoms.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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