Chemical Probes for Histamine Receptor Subtypes.

Autor: Falkenstein M; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf, Germany., Elek M; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf, Germany., Stark H; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf, Germany. stark@hhu.de.
Jazyk: angličtina
Zdroj: Current topics in behavioral neurosciences [Curr Top Behav Neurosci] 2022; Vol. 59, pp. 29-76.
DOI: 10.1007/7854_2021_254
Abstrakt: Ligands with different properties and different selectivity are highly needed for in vitro and in vivo studies on the (patho)physiological influence of the chemical mediator histamine and its receptor subtypes. A selection of well-described ligands for the different receptor subtypes and different studies is shown with a particular focus on affinity and selectivity. In addition, compounds with radioactive or fluorescence elements will be presented with their beneficial use for other species or different investigations.
(© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.)
Databáze: MEDLINE