The ATHENA COVID-19 Study: Cohort profile and first findings for people diagnosed with COVID-19 in Queensland, 1 January to 31 December 2020.

Autor: Welsh J; Research Fellow, Research School of Population Health, Australian National University, Canberra, Australian Capital Territory., Korda RJ; Senior Fellow, Research School of Population Health, Australian National University, Canberra, Australian Capital Territory., Paige E; Research Fellow, Research School of Population Health, Australian National University, Canberra, Australian Capital Territory., Morgan MA; Associate Dean, Professor of General Practice, Faculty of Science & Medicine, Bond University, Robina, Gold Coast, Queensland., Law HD; Research Fellow, Research School of Population Health, Australian National University, Canberra, Australian Capital Territory., Stanton T; Senior Staff Specialist, Cardiology, Sunshine Coast University Hospital, Queensland Health, Birtinya, Queensland., Bourne ZM; Director, Medicine on Maple, Maleny, Queensland., Tolosa MX; Senior Epidemiologist, Department of Health, Brisbane, Queensland., Greaves K; Senior Staff Specialist, Cardiologist, Principal Project Lead: The ATHENA COVID-19 Study, Sunshine Coast University Hospital, Birtinya, Queensland.; Senior Fellow, Research School of Population Health, Australian National University, Canberra, Australian Capital Territory.
Jazyk: angličtina
Zdroj: Communicable diseases intelligence (2018) [Commun Dis Intell (2018)] 2021 Sep 30; Vol. 45. Date of Electronic Publication: 2021 Sep 30.
DOI: 10.33321/cdi.2021.45.51
Abstrakt: Background: To date, there are limited Australian data on characteristics of people diagnosed with COVID-19 and on how these characteristics relate to outcomes. The ATHENA COVID-19 Study was established to describe health outcomes and investigate predictors of outcomes for all people diagnosed with COVID-19 in Queensland by linking COVID-19 notification, hospital, general practice and death registry data. This paper reports on the establishment and first findings for the ATHENA COVID-19 Study.
Methods: Part 1 of the ATHENA COVID-19 Study used Notifiable Conditions System data from 1 January 2020 to 31 December 2020, linked to: Emergency Department Collection data for the same period; Queensland Health Admitted Patient Data Collections (from 1 January 2010 to 30 January 2021); and Deaths Registrations data (from 1 January 2020 to 17 January 2021).
Results: To 31 December 2020, a total of 1,254 people had been diagnosed with SARS-CoV-2 infection in Queensland: half were female (49.8%); two-thirds (67.7%) were aged 20-59 years; and there was an over-representation of people living in less-disadvantaged areas. More than half of people diagnosed (57.6%) presented to an ED; 21.2% were admitted to hospital as an inpatient (median length of stay 11 days); 1.4% were admitted to an intensive care unit (82.4% of these required ventilation); and there were six deaths. Analysis of factors associated with these outcomes was limited due to small case numbers: people living in less-disadvantaged areas had a lower risk of being admitted to hospital (test for trend, p < 0.001), while those living in more remote areas were less likely than people living in major cities to present to an ED (test for trend: p=0.007), which may reflect differential health care access rather than health outcomes per se. Increasing age (test for trend, p < 0.001) and being a current/recent smoker (age-sex-adjusted relative risk: 1.61; 95% confidence interval: 1.00, 2.61) were associated with a higher risk of being admitted to hospital.
Conclusion: Despite uncertainty in our estimates due to small numbers, our findings are consistent with what is known about COVID-19. Our findings reinforce the value of linking multiple data sources to enhance reporting of outcomes for people diagnosed with COVID-19 and provide a platform for longer term follow-up.
(© Commonwealth of Australia CC BY-NC-ND.)
Databáze: MEDLINE