SARS-CoV-2 Supply Shortages and Tuberculosis Diagnostics: Current Issues Requiring Immediate Solutions.

Autor: Armstrong DT; The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA., Tacheny EA; MRIGlobal, Gaithersburg, Maryland, USA., Olinger G; MRIGlobal, Gaithersburg, Maryland, USA., Howard R; MRIGlobal, Gaithersburg, Maryland, USA., Lemmon MM; MRIGlobal, Gaithersburg, Maryland, USA., Dasgupta D; MRIGlobal, Gaithersburg, Maryland, USA., Eisemann E; The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA., Parrish N; The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
Jazyk: angličtina
Zdroj: Journal of clinical microbiology [J Clin Microbiol] 2021 Nov 18; Vol. 59 (12), pp. e0077821. Date of Electronic Publication: 2021 Sep 29.
DOI: 10.1128/JCM.00778-21
Abstrakt: The SARS-CoV-2 pandemic has strained manufacturing capacity worldwide, resulting in significant shortages of laboratory supplies both directly and indirectly. Such shortages include probe-based kits for detection of the Mycobacterium tuberculosis complex from positive liquid broth cultures. These shortages and possible loss of this particular assay have consequences for laboratory testing algorithms and public health in the United States. As there are no FDA-approved, commercially available options that currently exist which could immediately fill this gap, laboratories must identify alternatives and plan for modifying current testing algorithms to accommodate this change.
Databáze: MEDLINE