Two new sesquiterpenes from Xylopia vielana .

Autor: Chen L; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. China., Yang P; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. China., Zhang M; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. China., Dai W; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. China.
Jazyk: angličtina
Zdroj: Natural product research [Nat Prod Res] 2023 Apr; Vol. 37 (7), pp. 1199-1204. Date of Electronic Publication: 2021 Sep 29.
DOI: 10.1080/14786419.2021.1984907
Abstrakt: Two new sesquiterpenes ( 1 - 2 ) and six known analogues ( 3 - 8 ) were isolated from the branches and leaves of Xylopia vielana Pierre. The structures of the new compounds were identified by analyzing 1 D and 2 D NMR data and HRESIMS data, combined with induced and calculated circular dichroism experiments. In addition, compounds 1 - 4, 7 and 8 showed notable nitric oxide (NO) inhibitory effects (IC 50 < 10  μ M) on the model of the lipopolysaccharide (LPS)-activated RAW 264.7 macrophages.
Databáze: MEDLINE