( - )-Brunneusine, a new phenolic compound with antibacterial properties in aqueous medium from the leaves of Agelanthus brunneus (Engl.) Tiegh (LORANTHACEAE).
| Autor: | Thomas Wieland MK; Department of Organic Chemistry, University of Yaoundé I, Yaoundé, P.O. Box 812, Cameroon., Pantaleon A; Department of Organic Chemistry, University of Yaoundé I, Yaoundé, P.O. Box 812, Cameroon., Luciane Marlyse M; Department of Biology and Animal Physiology, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon., Bathelemy N; Department of Pharmacognosy and Pharmaceutical Chemistry, University of Yaoundé I, Yaoundé, P.O. Box 1364, Cameroon.; School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK., Thomas SE; School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK., Bonaventure NT; Department of Organic Chemistry, University of Yaoundé I, Yaoundé, P.O. Box 812, Cameroon., Richard SG; School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK. |
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| Jazyk: | angličtina |
| Zdroj: | Zeitschrift fur Naturforschung. C, Journal of biosciences [Z Naturforsch C J Biosci] 2021 Sep 28; Vol. 77 (3-4), pp. 157-165. Date of Electronic Publication: 2021 Sep 28 (Print Publication: 2022). |
| DOI: | 10.1515/znc-2021-0143 |
| Abstrakt: | Agelanthus brunneus (Loranthaceae) is a hemiparasitic plant growing on Senna siamea (Fabaceae). The chemical investigation of its leaves and flowers led to the isolation of one new phenolic compound namely (-)-brunneusine ( 1 ), together with 13 known compounds. The crude leaves and flowers extracts (CLE and CFLE) with their ethyl acetate fractions (EAFL and EAFFL) and some isolated compounds ( 1-3 ; 8-9 and 11-14 ) have been tested on four bacterial species of sanitary importance isolated in an aquatic environment. All the samples except compound 3 showed antibacterial activity with MICs ranging from 0.43 to 8.88.10 3 µg/mL and MBCs from 0.43 to 3.55.10 3 µg/mL. Compounds 9 and 14 showed better activity on all bacterial species tested with MICs ranging from 0.43 to 27.77 µg/mL. Only CLE, EAFL and compounds 14 , 2 , 8 and 9 showed bactericidal effects on all bacterial species tested. (© 2021 Walter de Gruyter GmbH, Berlin/Boston.) |
| Databáze: | MEDLINE |
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