Prevalence of extraintestinal manifestations in ulcerative colitis and associated risk factors.

Autor: Rawal KK; Prime Institute of Digestive Sciences, Panchvati Main Road, Rajkot, 360 004, India. kkrawal@gmail.com., Shukla VP; Prime Institute of Digestive Sciences, Panchvati Main Road, Rajkot, 360 004, India., Chikani S; Milestone Hospital, Vidyanagar Main Road, Rajkot, 360 002, India., Thakkar M; Retina Care Centre, Virani Chowk, Vidyanagar Main Road, Rajkot, 360 002, India., Ruparelia M; Devarsh, 13-Manhar Plot, Mangala Main Road, Rajkot, 360 002, India., Chudasama RK; Department of Community Medicine, PDU Government Medical College, Rajkot, 360 001, India.
Jazyk: angličtina
Zdroj: Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology [Indian J Gastroenterol] 2021 Oct; Vol. 40 (5), pp. 477-482. Date of Electronic Publication: 2021 Sep 27.
DOI: 10.1007/s12664-021-01181-9
Abstrakt: Background: The data on prevalence of extraintestinal manifestations (EIM) in ulcerative colitis (UC) are  scanty and highly variable.
Methods: Consecutive patients with UC were prospectively evaluated from November 2016 to August 2017. A detailed history was obtained and physical examination was done. Presence of EIM was confirmed by a consultant rheumatologist, ophthalmologist and dermatologist. Tests performed were hemogram, liver function test, abdominal ultrasound, slit lamp examination, X-ray and magnetic resonance imaging when deemed necessary.
Results: A total of 227 patients with UC were enrolled in this study. The prevalence of EIM was 7.92%. Mucocutaneous (4.84%) manifestations were the commonest, followed by musculoskeletal (1.32%) and ocular (0.88%). Hepatobiliary (0.44%) and vascular (0.44) manifestations were present in equal frequency. History of appendicectomy was associated with  EIM.
Conclusion: The prevalence of EIM in UC was low in our study. History of appendicectomy was a risk factor for EIM.
(© 2021. Indian Society of Gastroenterology.)
Databáze: MEDLINE