Biochemical, electrolytic, and cardiovascular evaluations in cats with urethral obstruction.

Autor: Canei DH; Program of Postgraduate in Veterinary Sciences, Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá - Mato Grosso, Brazil., Pereira ME; Program of Postgraduate in Veterinary Sciences, Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá - Mato Grosso, Brazil., de Freitas MN; Scientific Initiation Volunteer (CNPq), Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá - Mato Grosso, Brazil., Trevisan YPA; Program of Postgraduate in Veterinary Sciences, Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá - Mato Grosso, Brazil., Zorzo C; Program of Postgraduate in Veterinary Sciences, Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá - Mato Grosso, Brazil., Bortolini J; Department of Statistics, Federal University of Mato Grosso, Cuiabá - MT, Brazil., Mendonça AJ; Veterinary Hospital, Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá - Mato Grosso, Brazil., Sousa VRF; Veterinary Hospital, Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá - Mato Grosso, Brazil., Ferreira de Almeida ADBP; Veterinary Hospital, Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá - Mato Grosso, Brazil.
Jazyk: angličtina
Zdroj: Veterinary world [Vet World] 2021 Aug; Vol. 14 (8), pp. 2002-2008. Date of Electronic Publication: 2021 Aug 04.
DOI: 10.14202/vetworld.2021.2002-2008
Abstrakt: Background and Aim: Urethral obstruction (UO) is a common condition in feline medicine. Severe acid-base and electrolyte disorders promote relevant electrocardiographic changes in these animals. Cardiac biomarkers such as cardiac troponin I have been shown to be useful in identifying cats with myocardial disease, but it has not been investigated whether UO leads to myocardial damages. This study aimed to evaluate biochemical changes, electrocardiographic findings, troponin I measurements, and electrolyte disturbances for 7 days in cats with UO.
Materials and Methods: This follow-up prospective study included 33 cats diagnosed with UO for 7 days. For all cats, clinical examination, serum biochemistry, electrolyte analyses, blood pressure, and electrocardiography were performed. Cardiac troponin I was measured in the serum in 16 cats at 3 different times.
Results: The mean age of the feline population was 1.83±1.58 years (mean±standard deviation). Creatinine, urea, blood urea nitrogen, glucose, phosphorus, base excess, bicarbonate, and serum potassium decreased significantly (p≤0.05), while ionic calcium and blood pH increased significantly (p≤0.05) at different times. Electrocardiographic abnormalities were observed in 21/33 (63.63%) of the felines on admission day. The electrocardiographic abnormalities were no longer observed on the subsequent days. Only one feline showed changes in troponin I cardiac concentrations.
Conclusion: This study suggests the sum and severity of electrolyte abnormalities aggravate the clinical and cardiovascular status of these patients. However, cTnI, blood pressure, and heart rate within the reference range do not exclude the presence of major cardiovascular and metabolic abnormalities. The hyperglycemia in felines with UO appears to be associated with decreased renal clearance, which may reflect the severity of hyperkalemia and azotemia. The metabolic and cardiovascular changes of these felines are minimized by the establishment of appropriate intensive care; however, cardiac and blood gas monitoring is essential to assess the severity of the disease.
(Copyright: © Canei, et al.)
Databáze: MEDLINE
Externí odkaz: