Cardiovascular risk in the elderly population of Spain. The EPICARDIAN risk score.

Autor: Gabriel R; Departamento de Salud Internacional, Escuela Nacional de Sanidad, Instituto de Salud Carlos III, Madrid, Spain. Electronic address: rgabriel@isciii.es., Muñiz J; Instituto Universitario de Ciencias de la Salud, Universidad de La Coruña, A Coruña, Spain., Vega S; Centro de Salud de Arévalo, SACyL, Arévalo, Ávila, Spain., Moral I; Unidad de Investigación, EAP Sardenya-IIB, Barcelona, Spain., Pérez Castro TR; Instituto Universitario de Ciencias de la Salud, Universidad de La Coruña, A Coruña, Spain., Rodriguez-Salvanés F; Instituto de Investigación Sanitaria Hospital Universitario de La Princesa, Madrid, Spain., Suárez C; Instituto de Investigación Sanitaria Hospital Universitario de La Princesa, Madrid, Spain., Novella B; Instituto de Investigación Sanitaria Hospital Universitario de La Princesa, Madrid, Spain., Brotons C; Unidad de Investigación, EAP Sardenya-IIB, Barcelona, Spain.
Jazyk: angličtina
Zdroj: Revista clinica espanola [Rev Clin Esp (Barc)] 2022 Jan; Vol. 222 (1), pp. 13-21. Date of Electronic Publication: 2021 Sep 24.
DOI: 10.1016/j.rceng.2021.05.003
Abstrakt: Background and Objectives: Cardiovascular risk estimation in people over 70 years of age is problematic. Most scores have been created based on cohorts of middle-aged people, with an underrepresentation of older adults. The predictive power of classical cardiovascular risk factors declines with age. The aim of this work is to develop a specific score for estimating cardiovascular risk among the elderly population in Spain.
Methods: This work is a population-based cohort established in 1995.
Setting: Three geographical areas of Spain (Madrid, Ávila, and Lugo).
Participants: 3,729 people older than 64 years with no cardiovascular diseases (CVD) at baseline.
Measurements: Suspected fatal and nonfatal CVD (both coronary heart disease and stroke) were investigated annually and confirmed using the WHO-MONICA criteria. All participants were followed-up on until occurrence of a first CVD event, until death, or until December 31, 2015.
Results: Age was the strongest predictor of CVD at 10 years in both men and women. In men, variables associated with CVD were high blood pressure treatment (HR: 1.35; 95% CI: 1.067-1.710), diabetes (HR: 1.359; 95% CI: 0.997-1.852), and smoking (HR: 1.207; 95% CI: 0.945-1.541) and in women, the variables were smoking (HR: 1.881; 95% CI: 1.356-2.609) and diabetes (HR: 1.285; 95% CI: 0.967-1.707). Total cholesterol did not increase the risk of CVD in men or women. However, total cholesterol levels >200 mg/dL were inversely associated with 10-year risk of CVD in men and women.
Conclusions: In elderly Spanish men, total CVD at 10 years is significantly increased by age, diabetes, and antihypertensive treatment and in elderly Spanish women by diabetes and smoking. Total cholesterol levels did not increase the risk of CVD, particularly in males.
(Copyright © 2021 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.)
Databáze: MEDLINE
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