Angina bullosa haemorrhagica: A 14-year multi-institutional retrospective study from Brazil and literature review.

Autor: Silva-Cunha JL; Department of Oral Surgery and Pathology, School of Dentistry Universidade Federal de Minas Gerais (UFMG) Av. Presidente Antônio Carlos, 6627 CEP 31270-901, Pampulha, Belo Horizonte, MG, Brazil silviafsousa@ufmg.br., Cavalcante IL, Barros CC, Felix FA, Venturi LB, Rolim LS, Silva-Júnior CL, Sousa EM, da Silveira ÉJ, Agostini M, Romañach -J, Almeida OP
Jazyk: angličtina
Zdroj: Medicina oral, patologia oral y cirugia bucal [Med Oral Patol Oral Cir Bucal] 2022 Jan 01; Vol. 27 (1), pp. e35-e41. Date of Electronic Publication: 2022 Jan 01.
DOI: 10.4317/medoral.24870
Abstrakt: Background: Angina bullosa haemorrhagica (ABH) is characterized by the recurrent appearance of blood blisters on the oral mucosa, mainly in adults' soft palate. In general, the blisters rupture spontaneously, lacking the necessity for biopsy. We report the clinical features of 23 ABH cases, emphasizing the clinical behavior and the management of these conditions.
Material and Methods: A retrospective descriptive cross-sectional study was performed. A total of 12,727 clinical records of oral and maxillofacial lesions from four dental services in Brazil were analyzed. Clinical data were collected from the clinical records and evaluated.
Results: The series comprised 12 males (52.2%) and 11 females (47.8%), with a mean age of 56.8 ± 14.6 years (ranging: 24-82 years) and a 1.1:1 male-to-female ratio. Most of the lesions affected the soft palate (n = 15, 65.2%). Clinically, the lesions presented mainly as an asymptomatic (n = 17, 73.9%) blood-filled blister that ruptured after a few minutes or hours, leaving an erosion. The masticatory trauma was the most frequent triggering event. No patient had coagulation disorders. A biopsy was performed in only four cases (17.4%). Treatment was symptomatic with a favorable outcome.
Conclusions: ABH is still poorly documented in the literature, and its etiology remains uncertain. ABH mainly affects the soft palate of elderly adults and has a favorable evolution in a few days. The therapeutic approach is often focused only on the relief of symptoms. However, it can share some clinical features with more serious diseases. Therefore, clinicians must recognize these lesions to avoid misdiagnosis.
Databáze: MEDLINE