Association of Bacterial Vaginosis With Higher Vaginal Indole Levels.
| Autor: | Sharma J; From the Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL., Gupta K, Schwebke JR, Geisler WM, Muzny CA |
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| Jazyk: | angličtina |
| Zdroj: | Sexually transmitted diseases [Sex Transm Dis] 2022 Mar 01; Vol. 49 (3), pp. e53-e55. |
| DOI: | 10.1097/OLQ.0000000000001564 |
| Abstrakt: | Abstract: We adapted a simple hydroxylamine-based indole assay to detect indole from stored vaginal swab specimens from women with and without bacterial vaginosis (BV). Women with BV had significantly higher vaginal indole levels compared with women without BV (6451.5 vs 5632.4 μM; P = 0.01), suggesting that indole-producing bacteria are a component of BV. Competing Interests: Conflict of Interest: C.A.M. is a consultant for Lupin Pharmaceuticals, BioFire Diagnostics, Cepheid, and PhagoMed. She has also received research funding support from Lupin Pharmaceuticals, as well as speaker honoraria from Abbott Molecular, Cepheid, Roche Diagnostics, and Becton Dickinson. J.R.S. is consultant for Talis, Gedea, PhagoMed, and Hologic. W.M.G. has received speaker honoraria from Hologic, Inc. and Sanofi and research funding from Hologic, Inc. K.G. and J.S. declare no conflicts of interest. (Copyright © 2021 American Sexually Transmitted Diseases Association. All rights reserved.) |
| Databáze: | MEDLINE |
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