Intussusception in children under five years of age in Enugu, Nigeria.

Autor:	Tagbo BN; Institute of Child Health & Department of Paediatrics, University of Nigeria Teaching Hospital, Enugu, Nigeria., Ezomike UO; Department of Paediatric Surgery, University of Nigeria Teaching Hospital, Enugu, Nigeria., Odetunde OA; Department of Paediatric Surgery, Enugu State University Teaching Hospital, Enugu, Nigeria., Edelu BO; Department of Paediatrics, University of Nigeria Teaching Hospital, Enugu, Nigeria., Eke BC; Department of Paediatrics, University of Nigeria Teaching Hospital, Enugu, Nigeria., Amadi OF; Department of Paediatrics, Enugu State University Teaching Hospital, Enugu, Nigeria., Okeke IB; Department of Paediatrics, Enugu State University Teaching Hospital, Enugu, Nigeria., Ani O; Department of Paediatrics, Enugu State University Teaching Hospital, Enugu, Nigeria., Chukwubuike CM; Department of Microbiology, University of Nigeria Teaching Hospital, Enugu, Nigeria., Mwenda JM; World Health Organization, African Regional Office, Brazzaville, DRC., Ekenze SO; Department of Paediatric Surgery, University of Nigeria Teaching Hospital, Enugu, Nigeria.
Jazyk:	angličtina
Zdroj:	The Pan African medical journal [Pan Afr Med J] 2021 Aug 06; Vol. 39 (Suppl 1), pp. 9. Date of Electronic Publication: 2021 Aug 06 (Print Publication: 2021).
DOI:	10.11604/pamj.supp.2021.39.1.20811
Abstrakt:	Introduction: intussusception is the invagination of a segment of the bowel into a distal segment. It occurs predominantly in infants worldwide. Following documentation of increased incidence after introduction of the first rotavirus vaccine (Rotashield, Wyeth-Lederle), it has become a standard recommendation to maintain surveillance for intussusception as newer rotavirus vaccines are introduced into EPI. Nigeria plans to introduce rotavirus vaccine in 2020. Pre-vaccine introduction surveillance will serve as a baseline to understand the epidemiology of intussusception in Nigeria. Methods: from 2013 to 2017, prospective enrolment of under five children with intussusception was done following the WHO protocol and using the WHO case report form. Only children who met the Pan American Health Organization/World Health Organization (PAHO/WHO) protocol case definition for intussusception were enrolled. These children were monitored until discharge or death. Clinical features and outcome were recorded in the case report form. Results: a total of 63 cases were enrolled, with age range of 3 to 42 months (median: 6 months, IQR: 5-9 months). Majority were within 4-6 months and 96% were < 12 months old. There were 41 males and 22 females (male to female ratio of 1.9:1). Duration of symptoms before presentation ranged from 2 hours to 15 days (median: 72 hours). Fifty-seven patients had abdominal ultrasound and 52 patients (83%) had surgery. Case fatality rate was 9% and duration of hospitalization ranged from 1 to 30 days (median 10 days, IQR 8-15 days). Conclusion: intussusception occurred most commonly in infants but well beyond the proposed age for rotavirus vaccination in the population studied. Late presentation and surgical intervention were common. This data provides a good baseline description of the epidemiology of intussusception. Competing Interests: The authors declare no competing interests. (©Beckie Nnenna Tagbo et al.)
Databáze:	MEDLINE
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