A Rare Case of Malignant Pleural Mesothelioma in a Young Healthy Male Without Asbestos Exposure.

Autor: Khatib S; Internal Medicine, University of Missouri Kansas City School of Medicine, Kansas City, USA., Asad O; Internal Medicine, Jordan University of Science and Technology, Irbid, JOR., Asad H; Pulmonary and Critical Care, University of Missouri Kansas City School of Medicine, Kansas City, USA., Sabobeh T; Internal Medicine, University of Missouri Kansas City School of Medicine, Kansas City, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2021 Aug 15; Vol. 13 (8), pp. e17199. Date of Electronic Publication: 2021 Aug 15 (Print Publication: 2021).
DOI: 10.7759/cureus.17199
Abstrakt: Malignant pleural mesothelioma (MPM) is a highly aggressive malignant tumor that arises from mesothelial cells of pleural cavity. The main risk factor for MPM is asbestos exposure with most cases discovered in elderly males after a long latency period. However, here we report a rare case of MPM diagnosed in a healthy young male patient without significant asbestos exposure. We report the case of an otherwise healthy 47-year-old male who presented with one week of exertional dyspnea and chest pain. Chest X-ray showed unilateral large pleural effusion. Chest CT scan revealed confluent right hilar mass and pleural thickening. Pleural fluid analysis showed exudative features. Cytology was negative for malignant cells. Core tissue biopsy showed features of epithelioid mesothelioma. Although most cases of MPM have been reported in elderly male patients with significant asbestos exposure, more research is needed to explain the pathogenesis of MPM in young patients without asbestos exposure.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2021, Khatib et al.)
Databáze: MEDLINE