COVID-19 Infection in Sickle Cell Patients in a Developing Country: A Case Series.

Autor:	Silva-Pinto AC; Regional Blood Center, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil.; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil., Santos-Oliveira L; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil., Santos FLS; Regional Blood Center, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil.; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil., Kashima Haddad S; Regional Blood Center, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil., De Santis GC; Regional Blood Center, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil.; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil., do Tocantins Calado R; Regional Blood Center, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil.; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil.
Jazyk:	angličtina
Zdroj:	Acta haematologica [Acta Haematol] 2022; Vol. 145 (1), pp. 1-4. Date of Electronic Publication: 2021 Sep 17.
DOI:	10.1159/000519028
Abstrakt:	Sickle cell disease is characterized by vaso-occlusive phenomena and haemolytic anaemia. There is a significant concern that the overlap of COVID-19 lung disease with acute chest syndrome that occurs in sickle cell patients may result in serious complications. Case reports of sickle cell patients with COVID-19 have been published. Here, we present a case series of COVID-19 infection in sickle cell patients in a developing country (Brazil). Only 10 patients tested positive so far for SARS-CoV-2 of 600 patients followed at our institution, of which 8 needed hospitalization (one in the intensive care unit), with no deaths. Even in a middle-income country, COVID-19 was reported to be relatively mild in sickle cell patients. In relation to risk factors, blood type O seems to confer some protection against developing severe COVID-19, a finding that could guide clinicians to adopt more clinical surveillance for patients with non-O blood type in sickle cell patients. (© 2021 S. Karger AG, Basel.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu