Pupillary fluctuation amplitude before target presentation reflects short-term vigilance level in Psychomotor Vigilance Tasks.

Autor: Yamashita J; Access Operations Project, NTT Access Network Service Systems Laboratories, Nippon Telegraph and Telephone Corporation, Yokosuka, Kanagawa, Japan.; Department of Intelligence Science and Technology, Graduate School of Informatics, Kyoto University, Kyoto, Kyoto, Japan., Terashima H; Human Information Science Laboratory, NTT Communication Science Laboratories, Nippon Telegraph and Telephone Corporation, Atsugi, Kanagawa, Japan., Yoneya M; Human Information Science Laboratory, NTT Communication Science Laboratories, Nippon Telegraph and Telephone Corporation, Atsugi, Kanagawa, Japan., Maruya K; Human Information Science Laboratory, NTT Communication Science Laboratories, Nippon Telegraph and Telephone Corporation, Atsugi, Kanagawa, Japan., Koya H; Access Operations Project, NTT Access Network Service Systems Laboratories, Nippon Telegraph and Telephone Corporation, Yokosuka, Kanagawa, Japan., Oishi H; Access Operations Project, NTT Access Network Service Systems Laboratories, Nippon Telegraph and Telephone Corporation, Yokosuka, Kanagawa, Japan., Nakamura H; Access Operations Project, NTT Access Network Service Systems Laboratories, Nippon Telegraph and Telephone Corporation, Yokosuka, Kanagawa, Japan., Kumada T; Department of Intelligence Science and Technology, Graduate School of Informatics, Kyoto University, Kyoto, Kyoto, Japan.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2021 Sep 17; Vol. 16 (9), pp. e0256953. Date of Electronic Publication: 2021 Sep 17 (Print Publication: 2021).
DOI: 10.1371/journal.pone.0256953
Abstrakt: Our daily activities require vigilance. Therefore, it is useful to externally monitor and predict our vigilance level using a straightforward method. It is known that the vigilance level is linked to pupillary fluctuations via Locus Coeruleus and Norepinephrine (LC-NE) system. However, previous methods of estimating long-term vigilance require monitoring pupillary fluctuations at rest over a long period. We developed a method of predicting the short-term vigilance level by monitoring pupillary fluctuation for a shorter period consisting of several seconds. The LC activity also fluctuates at a timescale of seconds. Therefore, we hypothesized that the short-term vigilance level could be estimated using pupillary fluctuations in a short period and quantified their amplitude as the Micro-Pupillary Unrest Index (M-PUI). We found an intra-individual trial-by-trial positive correlation between Reaction Time (RT) reflecting the short-term vigilance level and M-PUI in the period immediately before the target onset in a Psychomotor Vigilance Task (PVT). This relationship was most evident when the fluctuation was smoothed by a Hanning window of approximately 50 to 100 ms (including cases of down-sampled data at 100 and 50 Hz), and M-PUI was calculated in the period up to one or two seconds before the target onset. These results suggest that M-PUI can monitor and predict fluctuating levels of vigilance. M-PUI is also useful for examining pupillary fluctuations in a short period for elucidating the psychophysiological mechanisms of short-term vigilance.
Competing Interests: The authors have read the journal’s policy and have the following competing interests: The authors, JY, HT, MY, KM, HK, HO, and HN, are paid employees of NTT. NTT has signed a joint research agreement with TK and provided a research grant. The authors would like to declare the following patents/patent applications associated with this research: PCT/JP2020/043246 and PCT/JP2021/008837. NTT has a pending patent (in Japan, and possibly in the United States, Europe, and China) for estimating task performance using the amplitude of pupillary fluctuations. This does not alter our adherence to PLOS ONE policies on sharing data and materials.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje