COVID-19 Vaccine-Induced Thrombotic Thrombocytopenia: A Case Series.
| Autor: | Alalwan AA; Renal Medicine, Portsmouth Hospitals University NHS Trust, Portsmouth, GBR., Abou Trabeh A; Renal Medicine, Portsmouth Hospitals University NHS Trust, Portsmouth, GBR., Premchandran D; Renal Medicine, Portsmouth Hospitals University NHS Trust, Portsmouth, GBR., Razeem M; Renal Medicine, Portsmouth Hospitals University NHS Trust, Portsmouth, GBR. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2021 Sep 10; Vol. 13 (9), pp. e17862. Date of Electronic Publication: 2021 Sep 10 (Print Publication: 2021). |
| DOI: | 10.7759/cureus.17862 |
| Abstrakt: | Vaccine-induced thrombotic thrombocytopenia is a life-threatening prothrombotic syndrome that has been associated with two adenoviral vector-based coronavirus disease 2019 (COVID-19) vaccines. Although it remains a rare disorder with relatively low incidence, awareness of this condition is crucial given the ongoing vaccination programs of millions around the world. In this case series, we report four cases of vaccine-induced thrombotic thrombocytopenia, diagnosed at Queen Alexandra Hospital, Portsmouth, United Kingdom. We also review the mechanism of this syndrome, its clinical presentation, diagnosis, and course of treatment with emphasis on the role of therapeutic plasma exchange. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Alalwan et al.) |
| Databáze: | MEDLINE |
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