Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion.

Autor: Elbeyli A; Tayfur Ata Sokmen Faculty of Medicine, Department of Ophthalmology, Mustafa Kemal University, Hatay, Turkey., Kurtul BE; Tayfur Ata Sokmen Faculty of Medicine, Department of Ophthalmology, Mustafa Kemal University, Hatay, Turkey., Ozcan DO; Tayfur Ata Sokmen Faculty of Medicine, Department of Ophthalmology, Mustafa Kemal University, Hatay, Turkey., Ozcan SC; Tayfur Ata Sokmen Faculty of Medicine, Department of Ophthalmology, Mustafa Kemal University, Hatay, Turkey., Dogan E; Department of Ophthalmology, Sakarya Training and Research Hospital, Sakarya, Turkey.
Jazyk: angličtina
Zdroj: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2022 Oct-Nov; Vol. 30 (7-8), pp. 1940-1944. Date of Electronic Publication: 2021 Sep 15.
DOI: 10.1080/09273948.2021.1976219
Abstrakt: Purpose: To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).
Methods: A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated.
Results: RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively.
Conclusion: RDW seems superior to other inflammatory indices to predict CRAO.
Databáze: MEDLINE
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