Azathioprine-induced alopecia: a rare adverse event, early marker of myelotoxicity.

Autor: Vázquez Rodríguez JA; UGC Aparato Digestivo, Hospital de Poniente, España., Merino Gallego E; UGC Aparato Digestivo, Hospital de Poniente., Baños Arévalo AJ; Dermatología, Hospital de Poniente., Gallardo Sánchez F; UGC Aparato Digestivo, Hospital de Poniente., Miras Lucas L; UGC Aparato Digestivo, Hospital de Poniente., Pérez González Á; UGC Aparato Digestivo, Hospital de Poniente.
Jazyk: angličtina
Zdroj: Revista espanola de enfermedades digestivas [Rev Esp Enferm Dig] 2022 Jan; Vol. 114 (1), pp. 63-64.
DOI: 10.17235/reed.2021.8175/2021
Abstrakt: Though not exempt from adverse events, azathioprine (AZA) is an inexpensive and effective drug in the induction and maintenance treatment of patients with inflammatory bowel disease. We present the case of a 20-year-old female patient with left-side ulcerative colitis in whom AZA was started at a dose of 1.5 mg/kg/day due to dependence on corticoids (thiopurine methyltransferase activity: 14.9 U/mL). Two weeks after starting treatment she began to report excessive hair loss, resulting in an almost complete loss of scalp hair.
Databáze: MEDLINE