Tessier 3 and 4 Clefts and Choanal Atresia: An Unusual Association?

Autor:	Tonello C; 344933University of São Paulo, Bauru, Brazil., Martins DANDP; 344933University of São Paulo, Bauru, Brazil., Baptista MAFB; 344933University of São Paulo, Bauru, Brazil., Mondelli F; 125291Nove de Julho University (UNINOVE), Bauru, Brazil., Kokitsu Nakata NM; 344933University of São Paulo, Bauru, Brazil., Feitosa LB; 344933University of São Paulo, Bauru, Brazil., Alonso N; 344933University of São Paulo, Bauru, Brazil.
Jazyk:	angličtina
Zdroj:	The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association [Cleft Palate Craniofac J] 2022 Oct; Vol. 59 (10), pp. 1228-1232. Date of Electronic Publication: 2021 Sep 13.
DOI:	10.1177/10556656211042172
Abstrakt:	Introduction: Craniofacial clefts are rare congenital anomalies that might involve both soft tissue and skeletal components. The association of Tessier cleft number 3 and 4 with choanal atresia appears to be unusual and only few clinical cases have been reported in published literature. Objectives: Report a series of 13 cases of choanal atresia in patients with Tessier numbers 3 or 4 clefts and the literature review on this topic. Methods: A literature review was undertaken via PUBMED database before April 2020 addressing the association between Tessier numbers 3 or 4 clefts and choanal atresia. Retrospective chart review of patients diagnosed with both comorbidities at a tertiary hospital expertised in craniofacial anomalies. Results: Literature review yielded 10 studies describing the relationship between choanal atresia and Tessier 3 and 4 facial clefts. We identified 98 patients diagnosed with medial oro-ocular facial clefts (Tessier 3 and 4) and 119 with choanal atresia at our institution over a 20 years time period. Altogether, 13 individuals were diagnosed with both malformations, 3 patients with number 3 cleft, and 10 patients with number 4 cleft. It represents 13.26% of the cases. Conclusion: This study highlights the features of Tessier 3 and 4 facial clefts associated with choanal atresia. Although the publications regarding this association are very scarce, the authors present the largest series of cases of Tessier number 3 and 4 clefts with choanal atresia showing that association between these conditions could be not so unusual.
Databáze:	MEDLINE
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