Comparative evaluation of Emblica officinalis as an etchant and an MMP inhibitor with orthophosphoric acid and chlorhexidine on the microshear bond strength of composite resin: an ex vivo study.
| Autor: | Rajkumar DS; Department of Conservative Dentistry and Endodontics, JSS Dental College and Hospital, JSS Academy of Higher Education & Research, Mysuru, India., Mariswamy AB; Department of Conservative Dentistry and Endodontics, JSS Dental College and Hospital, JSS Academy of Higher Education & Research, Mysuru, India. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Restorative dentistry & endodontics [Restor Dent Endod] 2021 Jun 08; Vol. 46 (3), pp. e36. Date of Electronic Publication: 2021 Jun 08 (Print Publication: 2021). |
| DOI: | 10.5395/rde.2021.46.e36 |
| Abstrakt: | Objectives: This study aimed to evaluate Emblica officinalis (Indian gooseberry or amla) as an acid etchant and matrix metalloproteinase (MMP) inhibitor, and to compare its effect on the microshear bond strength of composite resin with orthophosphoric acid (OPA) and 2% chlorhexidine (CHX) as an acid etchant and MMP inhibitor, respectively. Materials and Methods: The etching effect and MMP-inhibiting action of amla on dentin samples were confirmed by scanning electron microscopy (SEM) and gelatin zymography, respectively. Dentinal slabs (3 mm thick) from 80 extracted human molars were divided into 10 and 20 samples to form 2 control groups and 3 experimental groups. Groups 1, 2, and 4 were etched with OPA and groups 3 and 5 with amla juice. An MMP inhibitor was then applied: CHX for group 2 and amla extract for groups 4 and 5. Groups 1 and 3 received no MMP inhibitor. All specimens received a standardized bonding protocol and composite resin build-up, and were subjected to microshear bond strength testing. The force at which the fracture occurred was recorded and statistically analyzed. Results: Amla juice had a similar etching effect as a self-etch adhesive in SEM and 100% amla extract was found to inhibit MMP-9 by gelatin zymography. The microshear bond strength values of amla were lower than those obtained for OPA and CHX, but the difference was not statistically significant. Conclusions: Amla has a promising role as an acid etchant and MMP inhibitor, but further studies are necessary to substantiate its efficacy. Competing Interests: Conflict of Interest: No potential conflict of interest relevant to this article was reported. (Copyright © 2021. The Korean Academy of Conservative Dentistry.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|