Lymphopenia in Covid-19: A single center retrospective study of 589 cases.

Autor:	Ghizlane EA; Intensive Care Unit, Mohammed VI University Hospital Center, Oujda, Morocco.; Mohammed First University Oujda, Faculty of Medicine and Pharmacy, Oujda, Morocco., Manal M; Intensive Care Unit, Mohammed VI University Hospital Center, Oujda, Morocco.; Mohammed First University Oujda, Faculty of Medicine and Pharmacy, Oujda, Morocco., Abderrahim EK; Intensive Care Unit, Mohammed VI University Hospital Center, Oujda, Morocco.; Mohammed First University Oujda, Faculty of Medicine and Pharmacy, Oujda, Morocco., Abdelilah E; Intensive Care Unit, Mohammed VI University Hospital Center, Oujda, Morocco.; Mohammed First University Oujda, Faculty of Medicine and Pharmacy, Oujda, Morocco., Mohammed M; Intensive Care Unit, Mohammed VI University Hospital Center, Oujda, Morocco.; Mohammed First University Oujda, Faculty of Medicine and Pharmacy, Oujda, Morocco., Rajae A; Intensive Care Unit, Mohammed VI University Hospital Center, Oujda, Morocco.; Mohammed First University Oujda, Faculty of Medicine and Pharmacy, Oujda, Morocco., Amine BM; Intensive Care Unit, Mohammed VI University Hospital Center, Oujda, Morocco.; Mohammed First University Oujda, FMP Oujda, LAMCESM, Oujda, Morocco., Houssam B; Intensive Care Unit, Mohammed VI University Hospital Center, Oujda, Morocco.; Mohammed First University Oujda, Faculty of Medicine and Pharmacy, Oujda, Morocco., Naima A; Mohammed First University Oujda, FMP Oujda, LAMCESM, Oujda, Morocco., Brahim H; Intensive Care Unit, Mohammed VI University Hospital Center, Oujda, Morocco.; Mohammed First University Oujda, Faculty of Medicine and Pharmacy, Oujda, Morocco.; Mohammed First University Oujda, FMP Oujda, LAMCESM, Oujda, Morocco.; Mohammed First University Oujda, Faculty of Medicine and Pharmacy Oujda, LERCSP, Oujda, Morocco.
Jazyk:	angličtina
Zdroj:	Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2021 Sep; Vol. 69, pp. 102816. Date of Electronic Publication: 2021 Sep 08.
DOI:	10.1016/j.amsu.2021.102816
Abstrakt:	Background: Lymphopenia is one of features that helps identify patients with severe Covid-19. This retrospectively study analyzed the association of lymphopenia with the severity of COVID-19 infection, determinate the predictive factors of lymphopenia and the significance of mortality in patient with lymphopenia. Methods: This retrospective study included patients diagnosed with Covid-19 and admitted to intensive care unit of our university hospital center From Mars 1st 2020, to December 31st , 2020. Results: In this study, 589 patients were included, a group had lymphopenia with 357 cases (60.06%) and the non-lymphopenia group with 232 cases (39.4%). The median age of our patients having lymphopenia was 65 years (56-76). Hypertension and diabetes were noted in the majority of patients with lymphopenia than in the non-lymphopenia group. Lymphopenia was strongly correlated to the inflammatory biomarkers of COVID-19 and were significant. A significant correlation was found between lymphopenia group and CT scan. Lymphopenia was observed as an indicator of prolonged duration of hospitalization but was not significant. Conclusion: Analytical data from this retrospective study shows the importance in the association between lymphopenia and the severity of COVID-19 infection, hence the need for dynamic monitoring of the number of lymphocytes on admission and during hospitalization of these patients. Competing Interests: The authors state that they have no conflicts of interest for this case series. (© 2021 The Authors.)
Databáze:	MEDLINE
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