Prevalence and Determinants of Helicobacter Pylori Infection among Adult Dyspeptic Patients in Abuja, Nigeria.
| Autor: | Oreh AC; Department of Hospital Services, Federal Ministry of Health, Abuja, Nigeria.; Department of Family Medicine, Garki Hospital Abuja, Nigeria., Onu A; Department of Family Medicine, Garki Hospital Abuja, Nigeria., Moses AL; Department of Hospital Services, National Hospital Abuja, Nigeria. |
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| Jazyk: | angličtina |
| Zdroj: | West African journal of medicine [West Afr J Med] 2021 Aug 30; Vol. 38 (8), pp. 775-784. |
| Abstrakt: | Background: Helicobacter pylori is common in developing countries like Nigeria with significant morbidity and risk of mortality. With rising antimicrobial resistance, risk factors of infection should be explored to develop prevention strategies and improve the health of developing communities. Objective: To identify determinants and clinical correlates of H. pylori among study participants. Methods: We conducted a hospital-based cross-sectional study between May and July 2017 of 280 dyspeptic adults in Garki Hospital Abuja. They were tested using serum H. pylori Immunoglobulin G antibody test kits. Data on patient characteristics were collected using pre-tested interviewer administered questionnaires. The data were analysed using SPSS version 25. Logistic regression and odds ratios with 95% confidence intervals were computed to identify risk factors and clinical features associated with H. pylori infection. Results: The overall prevalence of H. pylori infection was 53.6%. H. pylori was positively associated with age and monthly income. Family history of dyspepsia (OR = 0.32: 95% CI = 0.13 to 0.78), regular consumption of fruits and vegetables (OR = 0.11: 95% CI = 0.046 - 0.281) and regular handwashing with soap and water (OR = 0.02: 95% CI = 0.006 -0.040) were found to be protective against H. pylori infection. Conclusion: There is a high H. pylori prevalence amongst patients with dyspepsia in Garki Hospital Abuja. Interventions to reduce the incidence of H. pylori infection should emphasise regular handwashing with soap and water and regular fruit and vegetable consumption. Competing Interests: The Authors declare that no competing interest exists. (Copyright © 2021 by West African Journal of Medicine.) |
| Databáze: | MEDLINE |
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