Multiple Sources of Introduction of North American Arabidopsis thaliana from across Eurasia.

Autor:	Shirsekar G; Max Planck Institute for Developmental Biology, Tübingen, Germany., Devos J; Max Planck Institute for Developmental Biology, Tübingen, Germany., Latorre SM; Max Planck Institute for Developmental Biology, Tübingen, Germany.; Centre for Life's Origin and Evolution, University College London, London, United Kingdom., Blaha A; Max Planck Institute for Developmental Biology, Tübingen, Germany., Queiroz Dias M; Max Planck Institute for Developmental Biology, Tübingen, Germany., González Hernando A; Max Planck Institute for Developmental Biology, Tübingen, Germany., Lundberg DS; Max Planck Institute for Developmental Biology, Tübingen, Germany., Burbano HA; Max Planck Institute for Developmental Biology, Tübingen, Germany.; Centre for Life's Origin and Evolution, University College London, London, United Kingdom., Fenster CB; Oak Lake Field Station, Department of Natural Resource Management, South Dakota State University, Brookings, SD, USA., Weigel D; Max Planck Institute for Developmental Biology, Tübingen, Germany.
Jazyk:	angličtina
Zdroj:	Molecular biology and evolution [Mol Biol Evol] 2021 Dec 09; Vol. 38 (12), pp. 5328-5344.
DOI:	10.1093/molbev/msab268
Abstrakt:	Large-scale movement of organisms across their habitable range, or migration, is an important evolutionary process that can shape genetic diversity and influence the adaptive spread of alleles. Although human migrations have been studied in great detail with modern and ancient genomes, recent anthropogenic influence on reducing the biogeographical constraints on the migration of nonnative species has presented opportunities in several study systems to ask the questions about how repeated introductions shape genetic diversity in the introduced range. We present an extensive overview of population structure of North American Arabidopsis thaliana by studying a set of 500 whole-genome sequenced and over 2,800 RAD-seq genotyped individuals in the context of global diversity represented by Afro-Eurasian genomes. We use methods based on haplotype and rare-allele sharing as well as phylogenetic modeling to identify likely sources of introductions of extant N. American A. thaliana from the native range in Africa and Eurasia. We find evidence of admixture among the introduced lineages having increased haplotype diversity and reduced mutational load. We also detect signals of selection in immune-system-related genes that may impart qualitative disease resistance to pathogens of bacterial and oomycete origin. We conclude that multiple introductions to a nonnative range can rapidly enhance the adaptive potential of a colonizing species by increasing haplotypic diversity through admixture. Our results lay the foundation for further investigations into the functional significance of admixture. (© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.)
Databáze:	MEDLINE
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