Effects of Bee Propolis on FBG, HbA1c, and Insulin Resistance in Healthy Volunteers

Autor: Alassaf FA; Mosul University College of Pharmacy, Department of Pharmacology and Toxicology, Mosul, Iraq, Jasim MHM; Mosul University College of Pharmacy, Department of Pharmaceutical Chemistry, Mosul, Iraq, Alfahad M; Mosul University College of Pharmacy, Department of Pharmaceutics, Mosul, Iraq, Qazzaz ME; Mosul University College of Pharmacy, Department of Pharmacognosy and Medicinal Plants, Mosul, Iraq, Abed MN; Mosul University College of Pharmacy, Department of Pharmaceutical Chemistry, Mosul, Iraq, Thanoon IA; Mosul University College of Medicine, Department of Pharmacology, Mosul, Iraq
Jazyk: angličtina
Zdroj: Turkish journal of pharmaceutical sciences [Turk J Pharm Sci] 2021 Sep 01; Vol. 18 (4), pp. 405-409.
DOI: 10.4274/tjps.galenos.2020.50024
Abstrakt: Objectives: Bee propolis is a natural substance that is used in traditional medicine due to its versatile pharmacological actions. This study evaluates whether short term use of bee propolis supplementation could have an impact on glycemic control in healthy individuals.
Materials and Methods: A single daily dose of 1000 mg of bee propolis was administered orally to a total of 34 healthy individuals for 60 days. Body weight, body mass index (BMI), fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c), and insulin resistance were measured in all participants before and after the use of bee propolis.
Results: The results of this study showed that bee propolis was associated with a significant increase in body weight and BMI of healthy volunteers. Bee propolis supplementation decreased FBG and HbA1c, but did not affect insulin resistance.
Conclusion: Based on these results, bee propolis supplementation has a potential effect on glycemic control in healthy individuals and this should be considered when using this supplement in medical conditions.
Databáze: MEDLINE