| Autor: |
Brian-D Adinma JI; Department of Obstetrics and Gynecology, Nnamdi Azikiwe University and Teaching Hospital (NAUTH), Nnewi, Nigeria.; Centre for health and allied legal and demographical development research and training (CHALADDRAT), Nnamdi Azikiwe University, Awka, Nigeria., Ahaneku JE; Department of Chemical Pathology, Nnamdi Azikiwe University, Nnewi, Nigeria., Adinma ED; Department of Community Medicine, Nnamdi Azikiwe University and Teaching Hospital, Nnewi, Nigeria., Ugboaja JO; Department of Obstetrics and Gynecology, Nnamdi Azikiwe University and Teaching Hospital (NAUTH), Nnewi, Nigeria., Okolie V; Department of Obstetrics and Gynecology, Nnamdi Azikiwe University and Teaching Hospital (NAUTH), Nnewi, Nigeria., Adinma-Obiajulu ND; Department of Obstetrics and Gynecology, Nnamdi Azikiwe University and Teaching Hospital (NAUTH), Nnewi, Nigeria., Edet MM; Centre for health and allied legal and demographical development research and training (CHALADDRAT), Nnamdi Azikiwe University, Awka, Nigeria. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology [J Obstet Gynaecol] 2022 May; Vol. 42 (4), pp. 580-586. Date of Electronic Publication: 2021 Sep 06. |
| DOI: |
10.1080/01443615.2021.1931068 |
| Abstrakt: |
In this prospective study on vitamin D and its associated factors conducted on 256 pregnant women from Anambra state of southeastern Nigeria, Vitamin D deficiency (VDD) occurred in 36 (14.1%). Vitamin D levels were significantly associated with parity, gestational age, social class, place of abode, skin colour, workplace location, and compliance to ANC drugs. Pregnant women with these features are considered to be at risk for vitamin D deficiency. The study however did not show any association between vitamin D and maternal age, social class of the pregnant women, and the season of the year. It is recommended that vitamin D supplementation be considered routinely for women with the risk factors - especially for the grandmultipara, women at term gestational age, women of dark complexion, those with indoor work location, and of urban habitat.Impact statement What is already known on this subject? Vitamin D is a fat-soluble vitamin primarily responsible for calcium and phosphorous homeostasis in the human body. it is derived in the human body both from endogenous sources through cutaneous synthesis following exposure to sunlight, and from endogenous conversion from pre-vitamin D to 25-hdroxycholecalciferol (25 (OH)D. Vitamin D is essential in pregnancy for maternal health, foetal skeletal growth and bone development. Vitamin D deficiency (VDD) in pregnancy occurs globally with a prevalence of 4.7% to as high as 80%. What do the results of this study add? This study shows that parity, gestational age, social class, place of domicile, skin colour, workplace location, and compliance to ANC drugs constitutes associated factors to vitamin D levels. What are the implications of these findings for clinical practice and/or further research? These findings imply that grandmultiparous pregnant women, women at term gestational age, of dark complexion, with indoor work location, and of urban habitat, by virtue of their relatively lower levels of vitamin D, should be considered for routine vitamin D supplementation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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