Collagen- and hyaluronic acid-based hydrogels and their biomedical applications.

Autor: Xu Q; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States., Torres JE; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States., Hakim M; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 47907, USA., Babiak PM; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States., Pal P; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States., Battistoni CM; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States., Nguyen M; Department of Biomedical Engineering, University of California Davis, Davis, California 95616, United States., Panitch A; Department of Biomedical Engineering, University of California Davis, Davis, California 95616, United States., Solorio L; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 47907, USA., Liu JC; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States.; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 47907, USA.
Jazyk: angličtina
Zdroj: Materials science & engineering. R, Reports : a review journal [Mater Sci Eng R Rep] 2021 Oct; Vol. 146. Date of Electronic Publication: 2021 Jul 30.
DOI: 10.1016/j.mser.2021.100641
Abstrakt: Hydrogels have been widely investigated in biomedical fields due to their similar physical and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid (HA) are the main components of the ECM in many tissues. As a result, hydrogels prepared from collagen and HA hold inherent advantages in mimicking the structure and function of the native ECM. Numerous studies have focused on the development of collagen and HA hydrogels and their biomedical applications. In this extensive review, we provide a summary and analysis of the sources, features, and modifications of collagen and HA. Specifically, we highlight the fabrication, properties, and potential biomedical applications as well as promising commercialization of hydrogels based on these two natural polymers.
Competing Interests: Declaration of Competing Interest The authors declare no competing financial interest.
Databáze: MEDLINE
Externí odkaz: