Effect of Dietary Lactobacillus casei on Physiometabolic Responses and Liver Histopathology in Common Carp (Cyprinus carpio) After Exposure to Iron Oxide Nanoparticles.

Autor: Hedayati SA; Faculty of Fisheries and Environmental Science, Gorgan University of Agricultural and Natural Resources, Gorgan, Iran., Sheikh Veisi R; Faculty of Fisheries and Environmental Science, Gorgan University of Agricultural and Natural Resources, Gorgan, Iran., Hosseini Shekarabi SP; Department of Fisheries, Science and Research Branch, Islamic Azad University, Tehran, Iran., Shahbazi Naserabad S; Department of Fisheries, Faculty of Natural Resources, University of Tehran, Karaj, Iran., Bagheri D; Department of Fisheries, Faculty of Agriculture and Natural Resources, Persian Gulf University, Bushehr, Iran., Ghafarifarsani H; Department of Fisheries, Faculty of Natural Resources, Urmia University, Urmia, Iran. hamed_ghafari@alumni.ut.ac.ir.
Jazyk: angličtina
Zdroj: Biological trace element research [Biol Trace Elem Res] 2022 Jul; Vol. 200 (7), pp. 3346-3354. Date of Electronic Publication: 2021 Aug 30.
DOI: 10.1007/s12011-021-02906-9
Abstrakt: A 60-day feeding trial was performed to assess the dietary effect of Lactobacillus casei as a probiotic supplement on some serum biochemical parameters and liver histopathology in common carp fry after exposure to iron oxide nanoparticles (IoNPs). Six treatments were prepared as follows: control (no IoNP exposure and no dietary probiotic), P6: 10 6  CFU/g probiotic diet, P7: 10 7  CFU/g probiotic diet, NPs: 0.15 mg/l IoNPs, NPs + P6: 0.15 mg/l IoNPs with 10 6  CFU/g probiotic diet, and NPs + P7: 0.15 mg/l IoNPs with 10 7  CFU/gprobiotic diet. Based on the results, serum aspartate aminotransferase and alanine aminotransferase levels were significantly increased in 0.15 mg/l IoNPs, P7, and NPs + P6 treatments compared to the control group. In addition, the examination of antioxidant enzymes showed a significant increase in the levels of cortisol and glutathione S-transferase as well as malondialdehyde level. IoNPs also caused significant histopathological changes in the fish liver during the experiment such as hyperemia in sinusoidal spaces, hepatocytes vacuolation and necrosis, pyknosis, and disruption of hepatic lobules and atrophy. Results revealed the protective effects of dietary L. casei to mitigate the adverse impacts of IoNPs on the physiological processes of common carp.
(© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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