Data on nucleoid-associated proteins isolated from Mycoplasma gallisepticum after intracellular infection.

Autor:	Zubov AI; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russian Federation., Ladygina VG; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russian Federation., Kovalchuk SI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation., Ziganshin RH; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation., Galyamina MA; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russian Federation., Pobeguts OV; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russian Federation., Fisunov GY; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russian Federation.
Jazyk:	angličtina
Zdroj:	Data in brief [Data Brief] 2021 Aug 14; Vol. 38, pp. 107289. Date of Electronic Publication: 2021 Aug 14 (Print Publication: 2021).
DOI:	10.1016/j.dib.2021.107289
Abstrakt:	Mycoplasma gallisepticum (M. gallisepticum) belongs to the class of Mollicutes. It causes chronic respiratory disease in avian species. It is characterized by lack of cell wall and reduced genome size. As a result of genome reduction, M. gallisepticum has a limited variety of DNA-binding proteins (DBP) and transcription factors. Consequently, the diversity of DNA-binding proteins and transcription factors (TF) in M. gallisepticum is limited in comparison with related bacteria such as Bacillus subtilis . Studies have shown, however, that mycoplasmas demonstrate a wide range of differential expression of genes in response to various stress factors, which promotes effective adaptation to unfavorable conditions. We assume that in the case of mycoplasmas, which are characterized by a combination of the reduction of known gene expression regulation systems and a high adaptive potential, the coordination of gene expression can be provided due to local changes in the structure and spatial organization of the chromosome. The study of the dynamic changes of the proteomic profile of M. gallisepticum nucleoid may assist in revealing its mechanisms of functioning, regulation of chromosome organization and stress adaptation including its changes upon invasion of the host cells. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that might affect the work described in this article. (© 2021 Published by Elsevier Inc.)
Databáze:	MEDLINE
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