A wide spectrum of neurological manifestations in pediatrics patients with the COVID-19 infection: a case series.

Autor: Krueger MB; Universidade Federal de São Paulo, São Paulo, Brazil. mari_bk@hotmail.com.; Hospital Infantil Albert Sabin, Street Tertuliano Sáles, 544 - Vila União, Fortaleza, Ceará, 60410-794, Brazil. mari_bk@hotmail.com., Montenegro RC; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceara, Fortaleza, Ceará, Brazil., de Araújo Coimbra PP; Hospital Geral de Fortaleza, Fortaleza, Ceará, Brazil., de Queiroz Lemos L; Hospital Infantil Albert Sabin, Street Tertuliano Sáles, 544 - Vila União, Fortaleza, Ceará, 60410-794, Brazil., Fiorenza RM; Hospital Infantil Albert Sabin, Street Tertuliano Sáles, 544 - Vila União, Fortaleza, Ceará, 60410-794, Brazil., da Silva Fernandes CJ; Hospital Geral de Fortaleza, Fortaleza, Ceará, Brazil., Pessoa MSL; Hospital Geral de Fortaleza, Fortaleza, Ceará, Brazil., Rodrigues CL; Hospital Geral de Fortaleza, Fortaleza, Ceará, Brazil., da Cruz CG; Hospital Infantil Albert Sabin, Street Tertuliano Sáles, 544 - Vila União, Fortaleza, Ceará, 60410-794, Brazil., de Araújo Verdiano V; Hospital Infantil Albert Sabin, Street Tertuliano Sáles, 544 - Vila União, Fortaleza, Ceará, 60410-794, Brazil., de Carvalho Araújo FM; Laboratório Central de Análises Clínicas, Fortaleza, Ceará, Brazil., Braga-Neto P; Division of Neurology, Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceara, Fortaleza, Ceará, Brazil.; Universidade Estadual Do Ceará, Fortaleza, Ceará, Brazil., Sobreira-Neto MA; Division of Neurology, Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceara, Fortaleza, Ceará, Brazil.
Jazyk: angličtina
Zdroj: Journal of neurovirology [J Neurovirol] 2021 Oct; Vol. 27 (5), pp. 782-786. Date of Electronic Publication: 2021 Aug 26.
DOI: 10.1007/s13365-021-01004-9
Abstrakt: Neurological symptoms in COVID-19 patients can also be found in the pediatric population, but they are usually described as mild symptoms. Herein, we described a case series of four pediatric patients with severe and highly heterogeneous central and peripheral nervous system manifestations. The objective was to report neurological manifestations of COVID-19 in children and adolescents. The design is case series. The participants are four children and adolescents with confirmed COVID-19. The main outcome and measures are as follows: Clinical data were gathered from electronic medical records, and data of all neurologic symptoms were checked by a trained neurologist. We reported four pediatric patients with COVID-19 and different neurologic symptoms. Case 1 was a 16-year-old girl with a sensory and motor polyradiculopathy with RT-qPCR for COVID-19 and dengue both detected in CSF that improved after appropriate treatment. Case 2 was a 15-year-old boy with Guillain-Barre syndrome and had good response after using human immunoglobulin. Case 3 was a 5-year-old girl with acute intracranial hypertension that improved after going through lumbar puncture and using acetazolamide. Case 4 was a 2-month-old male infant with focal epileptic seizures that recovered after antiepileptic treatment. We highlight the need to consider different neurologic manifestations as part of the COVID-19 clinical spectrum.
(© 2021. Journal of NeuroVirology, Inc.)
Databáze: MEDLINE
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